| Sequence 1: | NP_001262995.1 | Gene: | Tl / 43222 | FlyBaseID: | FBgn0262473 | Length: | 1117 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_057646.1 | Gene: | TLR7 / 51284 | HGNCID: | 15631 | Length: | 1049 | Species: | Homo sapiens |
| Alignment Length: | 1063 | Identity: | 239/1063 - (22%) |
|---|---|---|---|
| Similarity: | 413/1063 - (38%) | Gaps: | 266/1063 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 129 TLIFESDNLGMNITRQHLDRLHGLKRFRFTTRRLT--HIPANLLTDMRNLSHL---ELRANIEEM 188
Fly 189 P---------------SHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTK 238
Fly 239 HDFEGATSVLGIDIHDNG--------------IEQLPHDVFAHLTNVTDINLSANLFRSLPQGLF 289
Fly 290 DHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRL-------------------RAELQSLPG 335
Fly 336 DLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLT-HLPDSLFAH-TTNLTDLRLE 398
Fly 399 DNL----------------------LTGISGDIFS-----------NLGNLVTLVMSRNRLRTID 430
Fly 431 SRAFVSTNGLRHLHLDHNDI----DLQQPLLDIMLQTQINS------------------------ 467
Fly 468 ----------PFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYNNISSL--GYE----- 515
Fly 516 DLAFL--SQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRG 578
Fly 579 VHKPQYSRQFKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVRTYD 643
Fly 644 KAL---VINCHSGNLTHVP------RLPNLHKNMQLME-------------------LHLENNTL 680
Fly 681 LRLPSANTPGYESVTSLHLAGNNLTSI------DVDQLPTNLTHLDISWNHLQMLNATVL--GFL 737
Fly 738 NRTMKWRSVKLSGNPWMCDCTAKPLLLFTQDNFERI------------GDRNEMMCVNAEMPTRM 790
Fly 791 VELSTNDICPAEKGVFIALAVVIALTGLLAGFTAALYYKFQTEIKIWLYAHNLLLWFVTEEDLDK 855
Fly 856 DKKFDAFISYSHKDQSFIE---DYLVPQLEHGPQK-FQLCVHERDWLVGGHIPENIMRSVADSRR 916
Fly 917 TIIVLSQNFIKSEWARLEFRAAHRSALNEGRSRIIVIIYSDIGDVEKLDEELKAYLKM------N 975
Fly 976 TYLKW-----GDPWFWDKLRFAL 993 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Tl | NP_001262995.1 | LRR_8 | 174..233 | CDD:290566 | 19/76 (25%) |
| leucine-rich repeat | 176..198 | CDD:275380 | 8/39 (21%) | ||
| leucine-rich repeat | 199..222 | CDD:275380 | 6/22 (27%) | ||
| LRR_RI | 216..542 | CDD:238064 | 100/440 (23%) | ||
| LRR_8 | 221..281 | CDD:290566 | 19/73 (26%) | ||
| leucine-rich repeat | 223..270 | CDD:275380 | 15/60 (25%) | ||
| leucine-rich repeat | 271..294 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 295..320 | CDD:275380 | 8/24 (33%) | ||
| leucine-rich repeat | 321..343 | CDD:275380 | 9/40 (23%) | ||
| LRR_8 | 342..402 | CDD:290566 | 19/83 (23%) | ||
| leucine-rich repeat | 344..367 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 368..391 | CDD:275380 | 10/24 (42%) | ||
| LRR_8 | 390..450 | CDD:290566 | 17/92 (18%) | ||
| leucine-rich repeat | 392..415 | CDD:275380 | 9/55 (16%) | ||
| leucine-rich repeat | 416..439 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 440..474 | CDD:275380 | 8/71 (11%) | ||
| leucine-rich repeat | 475..498 | CDD:275380 | 8/22 (36%) | ||
| LRR_8 | 477..534 | CDD:290566 | 24/65 (37%) | ||
| leucine-rich repeat | 499..520 | CDD:275380 | 10/27 (37%) | ||
| leucine-rich repeat | 523..552 | CDD:275380 | 6/28 (21%) | ||
| LRRCT | 561..619 | CDD:214507 | 9/57 (16%) | ||
| LRRNT | 631..667 | CDD:214470 | 8/44 (18%) | ||
| leucine-rich repeat | 664..693 | CDD:275380 | 9/47 (19%) | ||
| LRR_8 | 669..726 | CDD:290566 | 18/81 (22%) | ||
| leucine-rich repeat | 694..715 | CDD:275380 | 6/26 (23%) | ||
| leucine-rich repeat | 716..737 | CDD:275380 | 8/22 (36%) | ||
| LRRCT | 751..800 | CDD:214507 | 9/60 (15%) | ||
| TIR | 858..996 | CDD:214587 | 47/151 (31%) | ||
| TLR7 | NP_057646.1 | leucine-rich repeat | 598..651 | CDD:275380 | 9/54 (17%) |
| LRR 21 | 619..644 | 5/25 (20%) | |||
| leucine-rich repeat | 621..643 | CDD:275380 | 5/22 (23%) | ||
| LRR 22 | 649..672 | 3/22 (14%) | |||
| leucine-rich repeat | 652..676 | CDD:275380 | 2/23 (9%) | ||
| LRR 23 | 674..697 | 6/23 (26%) | |||
| leucine-rich repeat | 677..700 | CDD:275380 | 4/23 (17%) | ||
| LRR 24 | 698..721 | 5/22 (23%) | |||
| leucine-rich repeat | 701..724 | CDD:275380 | 5/22 (23%) | ||
| LRR 25 | 723..745 | 5/21 (24%) | |||
| leucine-rich repeat | 725..748 | CDD:275380 | 5/22 (23%) | ||
| LRR 26 | 746..769 | 9/26 (35%) | |||
| leucine-rich repeat | 749..767 | CDD:275380 | 8/17 (47%) | ||
| PCC | 753..>837 | CDD:188093 | 18/88 (20%) | ||
| LRR 27 | 772..795 | 7/25 (28%) | |||
| TIR | 890..>993 | CDD:214587 | 35/108 (32%) | ||
| LRR 1 | 43..64 | 4/20 (20%) | |||
| leucine-rich repeat | 48..69 | CDD:275380 | 4/20 (20%) | ||
| LRR 2 | 65..87 | 6/21 (29%) | |||
| LRR_8 | 75..139 | CDD:404697 | 14/63 (22%) | ||
| leucine-rich repeat | 91..128 | CDD:275380 | 6/36 (17%) | ||
| LRR 3 | 110..126 | 1/15 (7%) | |||
| LRR 4 | 127..149 | 6/24 (25%) | |||
| leucine-rich repeat | 129..173 | CDD:275380 | 14/49 (29%) | ||
| LRR 5 | 151..170 | 5/21 (24%) | |||
| LRR 6 | 171..195 | 3/23 (13%) | |||
| PLN00113 | 191..>711 | CDD:215061 | 118/555 (21%) | ||
| LRR 7 | 203..226 | 6/25 (24%) | |||
| leucine-rich repeat | 206..225 | CDD:275380 | 4/21 (19%) | ||
| leucine-rich repeat | 227..250 | CDD:275380 | 8/24 (33%) | ||
| LRR 8 | 228..247 | 6/20 (30%) | |||
| LRR 9 | 248..275 | 5/26 (19%) | |||
| leucine-rich repeat | 251..291 | CDD:275380 | 9/40 (23%) | ||
| LRR 10 | 289..312 | 5/22 (23%) | |||
| leucine-rich repeat | 292..315 | CDD:275380 | 4/22 (18%) | ||
| LRR 11 | 314..337 | 9/22 (41%) | |||
| leucine-rich repeat | 316..341 | CDD:275380 | 10/24 (42%) | ||
| LRR 12 | 339..368 | 4/28 (14%) | |||
| leucine-rich repeat | 342..371 | CDD:275380 | 4/28 (14%) | ||
| LRR 13 | 369..392 | 3/22 (14%) | |||
| leucine-rich repeat | 372..398 | CDD:275380 | 5/25 (20%) | ||
| LRR 14 | 396..419 | 6/22 (27%) | |||
| leucine-rich repeat | 399..422 | CDD:275380 | 4/22 (18%) | ||
| LRR 15 | 421..443 | 5/21 (24%) | |||
| LRR | <488..775 | CDD:227223 | 74/317 (23%) | ||
| LRR 16 | 492..515 | 10/23 (43%) | |||
| leucine-rich repeat | 496..518 | CDD:275380 | 8/21 (38%) | ||
| LRR 17 | 516..540 | 9/23 (39%) | |||
| leucine-rich repeat | 519..543 | CDD:275380 | 9/23 (39%) | ||
| LRR 18 | 541..564 | 7/29 (24%) | |||
| leucine-rich repeat | 544..567 | CDD:275380 | 9/36 (25%) | ||
| LRR 19 | 566..588 | 5/36 (14%) | |||
| leucine-rich repeat | 568..597 | CDD:275380 | 5/36 (14%) | ||
| LRR 20 | 595..618 | 4/24 (17%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D147327at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.780 | |||||