Protein Alignment CG6420 and Wdr20

DIOPT Version :10

• Sequence 1: NP_651499.2
• Gene: CG6420 / 43218
• FlyBaseID: FBgn0039451
• Length: 909
• Species: Drosophila melanogaster
• Sequence 2: XP_063118084.1
• Gene: Wdr20 / 314453
• RGDID: 1306499
• Length: 674
• Species: Rattus norvegicus
• Alignment Length: 980
• Identity: 317/980 - (32%)
• Similarity: 394/980 - (40%)
• Gaps: 409/980 - (41%)

  Fly     1 MANQLDASVKDDLKTQFVTREGTYRLLTLSEYSRPNRVGYSSNQSSPQVRVSMVTLPSPAQGKLG 65
            ||.:......:::||||.||||.|:||..|||||||||.::|..|:| ||||.|.|.
  Rat     1 MATEGGGKEMNEIKTQFTTREGLYKLLPHSEYSRPNRVPFNSQGSNP-VRVSFVNLN-------- 56

  Fly    66 SDVGVGTPVGGGTAGANTTTTNGSSPGASPTGAAGASTAISNGGAGGDYSHSNHNSNSAGNNTVE 130
                                                                             
  Rat    57 ----------------------------------------------------------------- 56

  Fly   131 ARLGGGISMHSMMNGGVVDQNGVATNQVLGGDRICFNFGRDLYVYSFRGAKKGTEMSKPIDKKFY 195
                              ||:|       .|||:|||.||:||.|.::|.:|..::||||||:.|
  Rat    57 ------------------DQSG-------NGDRLCFNVGRELYFYIYKGVRKAADLSKPIDKRIY 96

  Fly   196 KGTNPSCHDFNISSATPTGAPLLVGFTTGQIQLVSPHVGPREVRKLFNE---------------- 244
            |||.|:|||||..:||.....|||||:.||:||:.|.  .:|..|||||
  Rat    97 KGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPI--KKETSKLFNEEGRDSATGKAECRPAC 159

  Fly   245 ----------------------------------------------------------ERLIDKT 251
                                                                      ||||||:
  Rat   160 QSHVVSLCLPHQTLPLPTCHIMRTYLRAPALPDVWCWYITPSDVWREWTVSSSYALQIERLIDKS 224

  Fly   252 KVTCLKWLPNSPHLFLAAHASGHLYLYNEELPCAATAPSYQPFKLGDGYTILTSKSKTTRNPLFK 316
            :|||:||:|.|..|||.||:||.:||||.|..|..|||.||..|.|:.:.:.|.|||:|||||.|
  Rat   225 RVTCVKWVPGSESLFLVAHSSGSMYLYNVEHTCGTTAPHYQLLKQGESFAVHTCKSKSTRNPLLK 289

  Fly   317 WVFSTDNCCVNEFCFSPCGSHLAVVSQDGFLRVFHYDTMELLGIARSYFGGFLCVCWSPDGKYIV 381
            |  :.....:|||.|||.|..||.||||||||||::|::||.|..:|||||.|||||||||||||
  Rat   290 W--TVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIV 352

  Fly   382 VGGEDDLVTVWSLHERRVVARGQGHRSWVSVVAFDPYTTSYTNWDGGDFSDDENQMNEYSHSREA 446
            .|||||||||||..:.||:|||.||:||||||||||||||....|..:||..:....:..|.
  Rat   353 TGGEDDLVTVWSFLDCRVIARGHGHKSWVSVVAFDPYTTSVEESDPMEFSGSDEDFQDLLHF--- 414

  Fly   447 RFSGDSTANGGFEGFDR-NSTPVHADRNGPHSASFRSDASSAEKLMSYRLGSVSQDTQICLWDIT 510
                         |.|| |||.....:        |:...|....::||.|||.||||:||||:|
  Rat   415 -------------GRDRANSTQSRLSK--------RNSTDSRPVSVTYRFGSVGQDTQLCLWDLT 458

  Fly   511 EDVLRHPLVLRQPANSERAYLNGGVDEEAEAEDGIKVIRPVAMSGQATGQQAESGSCSPTREAAG 575
            ||:| .|   .||.:..|.:.|                                         ..
  Rat   459 EDIL-FP---HQPLSRARTHTN-----------------------------------------VM 478

  Fly   576 GGTGNGAGEHSNSSSSKFSTANCTISSQSSPDDCDTEAATPASTSSNAGAGSVAGAGAVASTKQN 640
            ..|...||.:.||         .|....|.|.......:.|.|..||||
  Rat   479 NATSPPAGSNGNS---------VTTPGDSGPPPLPRSNSLPHSAVSNAG---------------- 518

  Fly   641 NRNHGTGNSIKFPNCISATKSDSIDGGGGSGSGQRPSQTTSGYNSKTSNSSNKSSNSGSGFSAFN 705
                              :||..:||...||
  Rat   519 ------------------SKSSVMDGAIASG---------------------------------- 531

  Fly   706 SLTQRLSNFSFLSSSEKKGAGYEGSHSTAHRQHRKAMSMLKSYNQHNHTGGHNNHSQSNNSSSSN 770
                 :|.|:.||..::|    |..|...|::                     |||
  Rat   532 -----VSKFATLSLHDRK----ERHHEKDHKR---------------------NHS--------- 557

  Fly   771 FGHSSTLDSNAAGAIGSSSTAHSFGSLKLSRSSHHSSLATAAHASGSAAGSGSGVSSFDPMQLIG 835
            .||.|                        |:||...:|.|.|..              ||.:.:|
  Rat   558 MGHIS------------------------SKSSDKLNLVTKAKT--------------DPAKTLG 584

  Fly   836 TPACPRFDECPLLEPLVCKKIAHERLTALIFREDCFLTACQDGFIYTWARPG--------HATHA 892
            |..|||.::.||||||:||||||||||.|:|.|||.:||||:|||.||||||        |:...
  Rat   585 TSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCLVTACQEGFICTWARPGKVLFPCPCHSRRL 649

  Fly   893 TQHLS 897
            |.||:
  Rat   650 TIHLT 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6420	NP_651499.2	WD40 repeat	208..249	CDD:293791	21/114 (18%)
		WD40 repeat	284..330	CDD:293791	21/45 (47%)
		WD40	<298..417	CDD:441893	78/118 (66%)
		WD40 repeat	369..404	CDD:293791	28/34 (82%)
Wdr20	XP_063118084.1	None