Protein Alignment CG6420 and bun62

DIOPT Version :9

• Sequence 1: NP_001287545.1
• Gene: CG6420 / 43218
• FlyBaseID: FBgn0039451
• Length: 909
• Species: Drosophila melanogaster
• Sequence 2: NP_594635.1
• Gene: bun62 / 2542950
• PomBaseID: SPAC12B10.03
• Length: 543
• Species: Schizosaccharomyces pombe
• Alignment Length: 612
• Identity: 148/612 - (24%)
• Similarity: 230/612 - (37%)
• Gaps: 190/612 - (31%)

  Fly    17 FVT-REGTYRLLTLSEYSRPNRVGYSSNQSSPQVRVSMVTLPSPAQGKLGSDVGVGTPVG----- 75
            |:| |||.|.|  ..|:    ::| ||::|:||:              .||.:...|||.
pombe    14 FLTAREGEYVL--KDEF----QLG-SSSRSTPQI--------------TGSPLDPNTPVKRLFFM 57

  Fly    76 ----------------------GGTAGANTTTTNGSSPGASPTGAAGASTAISNGGAGGDYSHSN 118
                                  ....|.:....|...|           :.:.|      |.:|.
pombe    58 RINIAQFSRWDYPYPREYIEELKKIHGVHHVEENRDVP-----------SILEN------YRNSK 105

  Fly   119 HNS-NSAGNNTVEARL------GGG--ISMHSMMNGGVVDQNGVATNQ--VLGGDRICFNFGRDL 172
            ..| |.:.:||...:|      .|.  |:..|.::......|.|.:.|  :.|...:..|..:..
pombe   106 RKSHNFSSSNTPYLKLHRPASRAGAPLINAKSFISSLTFHDNIVRSFQPSIHGKTFVFANHEKSF 170

  Fly   173 YVYSFRGAKKGTEMSKPIDKKFYKGTNPSCHDFNISSATPTGAPLLVGFTTGQIQLVSPHVGPRE 237
            |......|...:.:.    |..:...:|.|||.|..:.:|.|..:::||.||.:....| :..:.
pombe   171 YWLDVSAANSHSALL----KMEFPRASPVCHDINSFTKSPKGLDVIIGFDTGDVLWYDP-INFKY 230

  Fly   238 VRKLFNEERLIDKTKVTCLKWLPNSPHLFLAAHASGHLYLYNE---ELPCAATAPSYQPFKL--- 296
            :|  ||:...::.:.||.:||:......||.:..:|.|.||::   |.|.....|......|
pombe   231 LR--FNKNGQLNSSSVTAIKWVAGKDSQFLVSFRNGWLVLYDKYRHEQPLHIVVPEKNLKSLYLS 293

  Fly   297 GDG-YTILTS---KSKTTRNPLFKWVFSTDNCCVNEFCFSPCGSHLAVVSQDGFLRVFHYDTMEL 357
            ..| :.||.|   :.....||:..:.||...  :|.|||||...:||:||:.|.|::|.:....:
pombe   294 SPGTFNILISINHRDDRKLNPVACYAFSKSP--INGFCFSPDYQYLALVSERGTLKLFDFVKEHV 356

  Fly   358 LGIARSYFGGFLCVCWSPDGKYIVVGGEDDLVTVWSLHERRVVARGQGHRSWVSVVAFDPYTTSY 422
            |.:..|||.|..||.||||||:|.:||:||||:::|...|::|||.|||:|||:.|.||.:.
pombe   357 LDVFHSYFAGLTCVTWSPDGKFIAIGGKDDLVSIYSFPLRKLVARCQGHKSWVTDVIFDAWR--- 418

  Fly   423 TNWDGGDFSDDENQMNEYSHSREARFSGDSTANGGFEGFDRNSTPVHADRNGPHSASFRSDASSA 487
                    .||:|
pombe   419 --------CDDDN---------------------------------------------------- 423

  Fly   488 EKLMSYRLGSVSQDTQICLWDITEDVLRHP-----LVLRQPANSERA------------------ 529
                 ||:.||..|.::.|||.:...:..|     .|.....||:.|
pombe   424 -----YRIASVGLDRKLLLWDFSVSAIHRPKSAVYYVNHHSNNSKPAISDFDDVGDLTMGSEIDN 483

  Fly   530 --YLNGGVD-EEAEAEDGIKVIRPVAM 553
              |:||.:. ....:...|.||.|:.:
pombe   484 SNYVNGDITIHPTLSRSLIPVISPITI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6420	NP_001287545.1	WD40	<193..509	CDD:225201	94/325 (29%)
		WD40 repeat	208..249	CDD:293791	10/40 (25%)
		WD40 repeat	284..330	CDD:293791	11/52 (21%)
		WD40	<297..417	CDD:295369	54/123 (44%)
		WD40 repeat	369..404	CDD:293791	20/34 (59%)
bun62	NP_594635.1	WD40	89..522	CDD:225201	128/516 (25%)
		WD40	<322..541	CDD:295369	70/259 (27%)
		WD40 repeat	368..404	CDD:293791	20/35 (57%)
		WD40 repeat	409..445	CDD:293791	15/103 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2394
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I1132
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002009
OrthoInspector	1	1.000	-	-		oto101830
orthoMCL	1	0.900	-	-		OOG6_102737
Panther	1	1.100	-	-	LDO	PTHR14107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R157
SonicParanoid	1	1.000	-	-		X1319
TreeFam	0	0.000	Not matched by this tool.
	10	9.890