DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Yif1 and yif1b

DIOPT Version :9

Sequence 1:	NP_651498.1	Gene:	Yif1 / 43217	FlyBaseID:	FBgn0039450	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_001007335.2	Gene:	yif1b / 492462	ZFINID:	ZDB-GENE-041114-16	Length:	304	Species:	Danio rerio

Alignment Length:	315	Identity:	132/315 - (41%)
Similarity:	186/315 - (59%)	Gaps:	21/315 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PNLGQPSQHIQQPPQQQPGYGYGAPPPQQAAGPPTYGIGAPQPVAPPTGQYPQFAMFQQPI---V 139
            ||.....|....|..:..|.......|.|.....:.|:...:|  ...|:.|.....|..:   :
Zfish     5 PNQSGFRQRKLLPQVRMRGSAMEPSDPTQLFDDTSSGVNKHEP--GRVGKSPDVFSGQNLLSDPM 67

  Fly   140 QDMAMQYGQKLADQGKQIMENQFEKWVPVAKLKYYFAVDNAYVGRKLRLLFFPYMHKDWSLRYDQ 204
            .::||.||..||..||::|:...::::|::|||||||||..|||:||.||.|||||.:|.:.|.|
Zfish    68 SNLAMAYGSSLASHGKEMMDKNLDRFIPISKLKYYFAVDTVYVGKKLGLLVFPYMHDNWEVNYQQ 132

  Fly   205 EHPVQPRYDVNAPDLYLPTMGYITYVIVAGLLLGMQKRFSPEQLGIQASSAMAYSIFELVIYSLA 269
            :.||.||:|:||||||:|.||:||||:||||.||.|.|||||.||||||||:.:.|.|::...|:
Zfish   133 DTPVAPRFDINAPDLYIPVMGFITYVLVAGLALGTQNRFSPEILGIQASSALVWLIIEVLAVLLS 197

  Fly   270 LYVMNVKTSLKTLDLLAFTGYKYVNIVVCLMVSTLFFKSGYYIALAYTSFSFGFFMLRTLRTKLL 334
            ||::.|.|.|.|:||:||:|||||.::|.::...||.::|||:||.:...|...|.:||||.|:|
Zfish   198 LYLVTVNTDLTTIDLVAFSGYKYVGMIVGVVAGLLFGRTGYYLALLWFCASIFVFTIRTLRLKIL 262

  Fly   335 QDNSPAAPSGAINYDPYGNPQQFDYSGGKKR-KLYFLFMIVAGQALFAFLLSKHL 388
               |.||..|.:            ..|.|.: ::|....|.|.|.:|.:.|:.||
Zfish   263 ---SEAAAEGRL------------VRGTKNQLRMYLTMAIAAAQPVFMYWLTFHL 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yif1	NP_651498.1	YIF1	142..383	CDD:281822	117/241 (49%)
yif1b	NP_001007335.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..54		6/34 (18%)
yif1b	NP_001007335.2	YIF1	70..297	CDD:281822	117/241 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586854
Domainoid	1	1.000	235	1.000	Domainoid score	I2300
eggNOG	1	0.900	-	-		E1_COG5197
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H60114
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3336
OMA	1	1.010	-	-		QHG55435
OrthoDB	1	1.010	-	-		D1256839at2759
OrthoFinder	1	1.000	-	-		FOG0002277
OrthoInspector	1	1.000	-	-		otm26046
orthoMCL	1	0.900	-	-		OOG6_101876
Panther	1	1.100	-	-	LDO	PTHR14083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1884
SonicParanoid	1	1.000	-	-		X1506
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800