DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yif1 and Yif1b

DIOPT Version :9

Sequence 1:	NP_651498.1	Gene:	Yif1 / 43217	FlyBaseID:	FBgn0039450	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_942029.2	Gene:	Yif1b / 292768	RGDID:	735199	Length:	311	Species:	Rattus norvegicus

Alignment Length:	377	Identity:	142/377 - (37%)
Similarity:	200/377 - (53%)	Gaps:	79/377 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSAAGRPR----PPKRVSDVNAMGPSAPMMGGGATFMAPPTGPGILDPNMYGAPAPAPVNSYGFD 77
            ::.||.||    |.||                    ..|.:.||:.||:.:            ||
  Rat     7 AAPAGTPRLRKWPSKR--------------------RVPVSQPGMADPHQF------------FD 39

  Fly    78 PNLGQPSQHIQQPPQQQPGYGYGAPPPQQAAGPPTYGIGAPQPVAPPTGQYPQFAMFQQPIVQDM 142
            .....||:            |||..|...:.|.||....|....||               :.:|
  Rat    40 DTSSAPSR------------GYGGQPSPGSLGYPTSSSEAAFLAAP---------------MSNM 77

  Fly   143 AMQYGQKLADQGKQIMENQFEKWVPVAKLKYYFAVDNAYVGRKLRLLFFPYMHKDWSLRYDQEHP 207
            ||.||..||.|||::::...::::||:|||||||||..|||:||.||.|||:|:||.::|.|:.|
  Rat    78 AMAYGSSLAAQGKELVDKNIDRFIPVSKLKYYFAVDTVYVGKKLGLLVFPYLHQDWEVQYQQDTP 142

  Fly   208 VQPRYDVNAPDLYLPTMGYITYVIVAGLLLGMQKRFSPEQLGIQASSAMAYSIFELVIYSLALYV 272
            |.||:|:||||||:|.|.:|||::||||.||.|.||||:.||:|||||:|:...|:|...|:||:
  Rat   143 VAPRFDINAPDLYIPAMAFITYILVAGLALGTQDRFSPDLLGLQASSALAWLTLEVVAILLSLYL 207

  Fly   273 MNVKTSLKTLDLLAFTGYKYVNIVVCLMVSTLFFKSGYYIALAYTSFSFGFFMLRTLRTKLLQDN 337
            :.|.|.|.|:||:||.|||||.::..::...||.|.|||:.||:...|...||:||||.|:|
  Rat   208 VTVNTDLTTIDLVAFLGYKYVGMIGGVLTGLLFGKIGYYLVLAWCCVSIFVFMIRTLRLKIL--- 269

  Fly   338 SPAAPSGAINYDPYGNPQQFDYSGGKKR-KLYFLFMIVAGQALFAFLLSKHL 388
            :.||..|.            ...|.:.: ::|....:.|.|.:..:.|:.||
  Rat   270 AQAAAEGV------------PVRGARNQLRMYLTMAVAAAQPVLMYWLTFHL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yif1	NP_651498.1	YIF1	142..383	CDD:281822	113/241 (47%)
Yif1b	NP_942029.2	YIF1	73..306	CDD:397797	114/262 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345871
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H60114
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55435
OrthoDB	1	1.010	-	-		D1256839at2759
OrthoFinder	1	1.000	-	-		FOG0002277
OrthoInspector	1	1.000	-	-		otm45454
orthoMCL	1	0.900	-	-		OOG6_101876
Panther	1	1.100	-	-	LDO	PTHR14083
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1506
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.860