Protein Alignment amon and RRT12

DIOPT Version :10

• Sequence 1: NP_477318.1
• Gene: amon / 43215
• FlyBaseID: FBgn0023179
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_009974.1
• Gene: RRT12 / 850412
• SGDID: S000000641
• Length: 491
• Species: Saccharomyces cerevisiae
• Alignment Length: 295
• Identity: 74/295 - (25%)
• Similarity: 109/295 - (36%)
• Gaps: 80/295 - (27%)

  Fly   187 GKNVTTAIMDDGVDYMHPDLKFNYNAEASYDFSSNDPFPYPRYTDDWFNSHGTRCAGEV------ 245
            |::|...|||.|:...||:  |........|.:...      :.|.  |.|||..||.|
Yeast   165 GQDVNAYIMDTGIFADHPE--FEDRVIQGIDLTKEG------FGDQ--NGHGTHVAGLVGSKTYG 219

  Fly   246 AAARDN-------GICGVGVAYDSKIAGIRMLDQPYMTDLIEANSMGHEPHKIHIYSASWGPTDD 303
            ||.|.|       |..|.|.| .:.::|:..:.:       ....:.....|..:.:.|.|..
Yeast   220 AAKRVNLVEVKVLGKDGSGEA-SNVLSGLEFIVE-------HCTKVSRPQGKKCVANLSLGSF-- 274

  Fly   304 GKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWASGDGGEEDDCNCDGYAASMWTISINSAINDGQ 368
                   |:..:...|:|..|.    |.::|.|:|      :.|.|.|.||  ..|..:.|..|.
Yeast   275 -------RSPIINMAVEGAIEE----GIVFVAAAG------NFNLDAYWAS--PASAENVITVGA 320

  Fly   369 -NAHYDESCSSTLASTFSNGAKDPN---TGVATTDL----YGKCTTTHSGTSAAAPEAAGVFALA 425
             :.|.|     |:|. |||.....|   .||....|    |.. |...||||.:.|...||.|:.
Yeast   321 FDDHID-----TIAK-FSNWGPCVNIFAPGVEIESLSHLNYND-TLILSGTSMSTPIVTGVAAIL 378

  Fly   426 LE--ANPQLTWRDIQHLTVLTSKRNSLFDAKNRFH 458
            |.  ..|::..::|::|:           .:|.||
Yeast   379 LSKGIEPEMIAQEIEYLS-----------TRNVFH 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amon	NP_477318.1	S8_pro-domain	43..122	CDD:465126
		Peptidases_S8_Protein_convertases_Kexins_Fur in-lik	150..446	CDD:173789	71/281 (25%)
		Peptidases_S8_S53	<409..485	CDD:415849	15/52 (29%)
		P_proprotein	534..621	CDD:460225
RRT12	NP_009974.1	Peptidases_S8_PCSK9_ProteinaseK_like	130..398	CDD:173790	71/289 (25%)