| Sequence 1: | NP_477318.1 | Gene: | amon / 43215 | FlyBaseID: | FBgn0023179 | Length: | 654 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001358972.1 | Gene: | PCSK5 / 5125 | HGNCID: | 8747 | Length: | 1887 | Species: | Homo sapiens |
| Alignment Length: | 624 | Identity: | 270/624 - (43%) |
|---|---|---|---|
| Similarity: | 364/624 - (58%) | Gaps: | 59/624 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 39 VFTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKH-RTLPHARSRRSLTHTRAL 102
Fly 103 KS----HPAVHTAVQQPGFKRVKRGLRPAVPAIHGMKFDLKVGEGNRIDEEPTDPYFPMQWYLKN 163
Fly 164 TGQNGGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDLKFNYNAEASYDFSSNDPFPYPR 228
Fly 229 YTDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQPYMTDLIEANSMGHEPHKIHI 293
Fly 294 YSASWGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWASGDGG-EEDDCNCDGYAASMWT 357
Fly 358 ISINSAINDGQNAHYDESCSSTLASTFSNGAKDPNTGVATTDLYGKCTTTHSGTSAAAPEAAGVF 422
Fly 423 ALALEANPQLTWRDIQHLTVLTSKRNSLFDAKNRFHWTMNGVGLEFNHLFGFGVLDAGAMVTLSK 487
Fly 488 QWHSVPPRYHCEAG-----ELTQPQAIVMGRSLFWEIKTDACK-GTDTEVNYLEHVQAVISANAS 546
Fly 547 RRGDLELFLTSPMGTKSMILSRRANDDDHRDGFTKWPFMTTHSWGEYPQGTWKLEARFNSPQTRH 611
Fly 612 ----GNLLEWSLVLHGTKEAPYRTLHPSSPHSKLAIVKK 646 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| amon | NP_477318.1 | S8_pro-domain | 43..122 | CDD:293079 | 28/83 (34%) |
| Peptidases_S8_Protein_convertases_Kexins_Fur in-like | 150..446 | CDD:173789 | 157/296 (53%) | ||
| Peptidase_S8 | 187..459 | CDD:278510 | 148/272 (54%) | ||
| Peptidases_S8_S53 | <409..485 | CDD:299169 | 42/75 (56%) | ||
| P_proprotein | 534..621 | CDD:279782 | 42/90 (47%) | ||
| PCSK5 | NP_001358972.1 | S8_pro-domain | 38..114 | CDD:374560 | 28/83 (34%) |
| Peptidases_S8_Protein_convertases_Kexins_Fur in-lik | 126..420 | CDD:173789 | 157/300 (52%) | ||
| P_proprotein | 505..595 | CDD:366670 | 42/90 (47%) | ||
| Cell attachment site. /evidence=ECO:0000255 | 519..521 | 1/1 (100%) | |||
| FU 1 | 630..680 | ||||
| GF_recep_IV | 635..744 | CDD:373332 | |||
| VSP | 724..1100 | CDD:146106 | |||
| FU | 1084..1129 | CDD:238021 | |||
| FU | 1126..1162 | CDD:214589 | |||
| FU | 1209..1256 | CDD:238021 | |||
| VSP | 1291..>1576 | CDD:146106 | |||
| GF_recep_IV | 1596..1713 | CDD:373332 | |||
| FU | 1695..1736 | CDD:214589 | |||
| AC 1. /evidence=ECO:0000250 | 1834..1853 | ||||
| AC 2. /evidence=ECO:0000250 | 1865..1887 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1404 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D311719at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000204 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.780 | |||||