DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amon and S1P

DIOPT Version :9

Sequence 1:	NP_477318.1	Gene:	amon / 43215	FlyBaseID:	FBgn0023179	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_649337.2	Gene:	S1P / 40399	FlyBaseID:	FBgn0037105	Length:	1012	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	87/404 - (21%)
Similarity:	141/404 - (34%)	Gaps:	120/404 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 LKSHPAVHTAVQQPGFKRVKRGLRPAVPAIHGMKFDLKVGEGNRIDEEPTDPYFPMQWYLKNTGQ 166
            |::||:|...|.|...:|:             :.:| .......|...|       |..|:|...
  Fly    93 LQTHPSVKAVVPQRSVRRI-------------LNYD-AYSNLTYIHRHP-------QGVLRNRNP 136

  Fly   167 NGGKVR-----LDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDL-----KFNYNAEASYDFSSN 221
            |..:.|     |..|:  .|..|||||.|..||.|.|:...||..     :.|:..|.|.|...
  Fly   137 NNDRHRQLCSVLHANI--LWKLGITGKGVKVAIFDTGLTKNHPHFRNVKERTNWTNEKSLDDRV- 198

  Fly   222 DPFPYPRYTDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQ---PYMTDLIEANS 283
                          ||||..||.:|::|:   | :|.|.|:.:...::...   .|.:..::|.:
  Fly   199 --------------SHGTFVAGVIASSRE---C-LGFAPDADLYIFKVFTNSQVSYTSWFLDAFN 245

  Fly   284 MGHEPHKIHIYSASWGPTD--DGKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWASGDGGEEDDC 346
            .... .||:|.:.|.|..|  |...|:.....:...::.....|.:  |.:|...:..|.:.|..
  Fly   246 YAIY-RKINILNLSIGGPDFMDSPFVEKVLELSANNVIMISAAGND--GPLYGTLNNPGDQSDVV 307

  Fly   347 NCDGYAASMWTISINSAINDGQNAHYDESCSSTLASTFSNGAKDPNTGVATTDL---YGK----- 403
            ...|                   ..:|:..           ||..:.|:.|.:|   ||:
  Fly   308 GVGG-------------------IQFDDKI-----------AKFSSRGMTTWELPLGYGRMGLDI 342

  Fly   404 ---------------CTTTHSGTSAAAPEAAGVFALALEANPQLTWRDIQHLTVLTSKRNSLFDA 453
                           |... ||||.::|..||..||.:..    .::.|.::...:.|:..:..|
  Fly   343 VTYGSQVEGSDVRKGCRRL-SGTSVSSPVVAGAAALLISG----AFQKIDYINPASLKQVLIEGA 402

  Fly   454 KNRFHWTM--NGVG 465
            :...|:.|  .|.|
  Fly   403 EKLPHYNMFEQGAG 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amon	NP_477318.1	S8_pro-domain	43..122	CDD:293079	7/19 (37%)
		Peptidases_S8_Protein_convertases_Kexins_Fur in-like	150..446	CDD:173789	72/333 (22%)
		Peptidase_S8	187..459	CDD:278510	62/304 (20%)
		Peptidases_S8_S53	<409..485	CDD:299169	16/59 (27%)
		P_proprotein	534..621	CDD:279782
S1P	NP_649337.2	Peptidases_S8_SKI-1_like	154..407	CDD:173805	66/309 (21%)
		Peptidase_S8	160..416	CDD:278510	65/312 (21%)
		DUF4350	610..673	CDD:290957
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1404
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740