DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amon and RSPO4

DIOPT Version :9

Sequence 1:	NP_477318.1	Gene:	amon / 43215	FlyBaseID:	FBgn0023179	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	XP_016883328.1	Gene:	RSPO4 / 343637	HGNCID:	16175	Length:	266	Species:	Homo sapiens

Alignment Length:	91	Identity:	21/91 - (23%)
Similarity:	24/91 - (26%)	Gaps:	38/91 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 GQNAHYDESCSSTLASTFSNGAKDPNTGVATTD----------LY-GKC-------TTTHSGTSA 413
            ||..:..:.|.:|..|.||.            |          || |||       |..|..|..
Human    82 GQEVNRCKKCGATCESCFSQ------------DFCIRCKRQFYLYKGKCLPTCPPGTLAHQNTRE 134

  Fly   414 AAPEAAGVFALALEANPQLTWRDIQH 439
            ...|.        |..|...|....|
Human   135 CQGEC--------ELGPWGGWSPCTH 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amon	NP_477318.1	S8_pro-domain	43..122	CDD:293079
		Peptidases_S8_Protein_convertases_Kexins_Fur in-like	150..446	CDD:173789	21/91 (23%)
		Peptidase_S8	187..459	CDD:278510	21/91 (23%)
		Peptidases_S8_S53	<409..485	CDD:299169	6/31 (19%)
		P_proprotein	534..621	CDD:279782
RSPO4	XP_016883328.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900