Protein Alignment amon and aex-5

DIOPT Version :9

• Sequence 1: NP_477318.1
• Gene: amon / 43215
• FlyBaseID: FBgn0023179
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_493594.1
• Gene: aex-5 / 173358
• WormBaseID: WBGene00000088
• Length: 537
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 178/564 - (31%)
• Similarity: 272/564 - (48%)
• Gaps: 83/564 - (14%)

  Fly    44 FLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRTLPHARSRRSLTHTRALKSHPAV 108
            ||.:. ..:|...|..:..::||            |..:|                  |:|:..|
 Worm    25 FLAKI-TSIDEHDARKIGRRFGF------------EAQWK------------------LQSYTDV 58

  Fly   109 HTAVQQPGFKRVKRGLRPAVPA----IHGMKFDLKVGEGNRIDEEP-TDPYFPMQ-WYLKNTGQN 167
            :...:   .:|.|||:...:.|    ...::|..|:....|....| |:..:|:. |.|..:
 Worm    59 YVGRR---LRRRKRGIEDEIVAEMMLSQQVQFIEKLQGFRRYKRAPMTNKGYPVHVWNLTPS--- 117

  Fly   168 GGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDLKFNYNAEASYDFSSNDPFPYPRYTDD 232
                   |.::.||..|.....||.|::|||||..|.|||..::...|:||......|.|:.:.:
 Worm   118 -------LYIREAWEDGFNASRVTVAVVDDGVDIKHVDLKSAFSPRVSFDFVRFGDLPTPKNSKE 175

  Fly   233 WFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQPYMTDLIEANSMGHEPHKIHIYSAS 297
            :  .|||:|||.|  |.:...||:||.:.:.:..|::|.|.::.|.:|.:::..:...|.|||.|
 Worm   176 F--EHGTQCAGLV--AMEGQQCGLGVGHGATLGAIKLLGQDFLNDALEGDALAFQKDLIDIYSVS 236

  Fly   298 WGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWASGDGG-EEDDCNCDGYAASMWTISIN 361
            |||.||||:.:.|...|..||..|...||||.|||:|||||:|| ..|:|..|||.::.:|:|..
 Worm   237 WGPKDDGKSAEKPAKFTEEAIKNGALHGRNGKGNIFVWASGNGGVNGDNCAYDGYVSNEYTLSFG 301

  Fly   362 SAINDGQNAHYDESCSSTLASTFSNGAKDPNTGVATTDLYGKCTTTHSGTSAAAPEAAGVFALAL 426
            .....|..|.|.|.|||.||:.....|....||:.:|     |::. ||:||:|..|:|:.:|.|
 Worm   302 VIDASGAPAAYGEGCSSVLAAVSGGDAMIQTTGLEST-----CSSI-SGSSASAAIASGIISLVL 360

  Fly   427 EANPQLTWRDIQHLTVLTSKRNSLFDAKNRFHWTMNGVGLEFNHLFGFGVLDAGAMVTLSKQWHS 491
            :|||.|:.||||||...||..:::.|.:    ...|..||.|:...|||:|:|..:|.::..|.:
 Worm   361 DANPTLSQRDIQHLIARTSNASAIRDVE----LYENSAGLNFHPKVGFGLLNAQKLVVMAATWEN 421

  Fly   492 VPPRYHCEAGELTQPQAIVMGRSLFWEIKTDACKGTDTEVNYLEHVQAVISANASRRGDLELFLT 556
            |.|:..||  ::.....|:              ..:|.:|..:|.|....|.....||.:::.|.
 Worm   422 VAPQVTCE--KMNLANGII--------------DNSDCDVTKVERVIVSGSIIHPHRGQVQIRLE 470

  Fly   557 SPMGTKSMILSRRANDDDHRDGFTKWPFMTTHSWGEYPQGTWKL 600
            ||.||.|.:|..|..|.. || ...|.|::.:.:||..:|.|||
 Worm   471 SPRGTISELLPLRPKDTS-RD-LLDWNFVSVNFFGENSRGIWKL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amon	NP_477318.1	S8_pro-domain	43..122	CDD:293079	12/77 (16%)
		Peptidases_S8_Protein_convertases_Kexins_Fur in-like	150..446	CDD:173789	115/298 (39%)
		Peptidase_S8	187..459	CDD:278510	108/272 (40%)
		Peptidases_S8_S53	<409..485	CDD:299169	32/75 (43%)
		P_proprotein	534..621	CDD:279782	24/67 (36%)
aex-5	NP_493594.1	Peptidases_S8_Protein_convertases_Kexins_Fur in-lik	116..379	CDD:173789	109/282 (39%)
		P_proprotein	448..532	CDD:307572	24/67 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1029
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D308083at2759
OrthoFinder	1	1.000	-	-		FOG0000204
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.770