DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beat-VII and Cd80

DIOPT Version :9

Sequence 1:	NP_733162.2	Gene:	beat-VII / 43213	FlyBaseID:	FBgn0250908	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_036015651.1	Gene:	Cd80 / 12519	MGIID:	101775	Length:	314	Species:	Mus musculus

Alignment Length:	184	Identity:	38/184 - (20%)
Similarity:	72/184 - (39%)	Gaps:	47/184 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VLVNLVVPRYVERGSSATFKCTHNVRPEILF--------------KVTWLKVDKGKFFEFINGRN 75
            :|:.:::.|..:..|....:.:.:|:.::|.              ::.|.|.|| .....|.|:.
Mouse    30 ILLFVLLIRLSQVSSDVDEQLSKSVKDKVLLPCRYNSPHEDESEDRIYWQKHDK-VVLSVIAGKL 93

  Fly    76 ---PPFRNSTIEGAEIDWDNSNEQQVTLKDVQFDLSGQFYC----------EVSTDTPIFTKASA 127
               |.::|.|:      :||:....:.|..|..| .|.:.|          ||.....:.....|
Mouse    94 KVWPEYKNRTL------YDNTTYSLIILGLVLSD-RGTYSCVVQKKERGTYEVKHLALVKLSIKA 151

  Fly   128 DELMSVFLPQTGPPTIKFRKRTPFAVGEKLFALCNTTRGRPAPHITWLINGKKV 181
            | ..:..:.::|.|:...::.|.||.|           |.|.|..:||.||:::
Mouse   152 D-FSTPNITESGNPSADTKRITCFASG-----------GFPKPRFSWLENGREL 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-VII	NP_733162.2	Ig	31..118	CDD:299845	22/113 (19%)
		IG_like	34..118	CDD:214653	21/110 (19%)
		Ig	141..>183	CDD:299845	12/41 (29%)
Cd80	XP_036015651.1	IgV_CD80	47..150	CDD:319335	20/110 (18%)
		Ig strand B	58..62	CDD:319335	1/3 (33%)
		Ig strand C	75..79	CDD:319335	0/3 (0%)
		Ig strand E	110..114	CDD:319335	0/3 (0%)
		Ig strand F	124..129	CDD:319335	1/4 (25%)
		Ig strand G	142..145	CDD:319335	0/2 (0%)
		IgC1_CD80	153..243	CDD:409505	13/52 (25%)
		Ig strand B	169..173	CDD:409505	0/3 (0%)
		Ig strand C	183..187	CDD:409505	0/3 (0%)
		Ig strand E	213..217	CDD:409505
		Ig strand F	224..229	CDD:409505
		Ig strand G	237..240	CDD:409505
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2D8C9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900