DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beat-VII and cd80

DIOPT Version :9

Sequence 1:	NP_733162.2	Gene:	beat-VII / 43213	FlyBaseID:	FBgn0250908	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_031752272.1	Gene:	cd80 / 101733943	-ID:	-	Length:	264	Species:	Xenopus tropicalis

Alignment Length:	190	Identity:	42/190 - (22%)
Similarity:	69/190 - (36%)	Gaps:	49/190 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FWIIALL-LGLQQTKPINGQSDVLVNLVVPRYVERGSSATFKC--------THNVRPEILFKVTW 59
            |.:.|:| .|:.:..||:.|  |..:.::|..|...|.:.::.        .|..|..::|..:.
Frog    14 FVLCAVLSAGVARQVPISAQ--VGASAILPCDVPTPSDSQWETLRLFVQRQNHGDRETVVFSFSE 76

  Fly    60 LKVDKGKFFEFINGRNPPFR-NSTIEGAEI-DWDNSNEQQVTLKDVQFDLSGQFYCEV------S 116
            .....|........|...|| |:::..:.| .||                .||:.|.|      .
Frog    77 NAEQTGHQTPRYRNRTHLFRHNASLSLSHIHPWD----------------EGQYVCHVFLRDKGE 125

  Fly   117 TDTPIFTKASADELMSVFLPQTGPPTIKFRKRTPFAVGEKLFALCNTTRGRPAPHITWLI 176
            ...|:.||.|    :||: .....|.|:.|.      ||   |.|.:..|.|...::|.:
Frog   126 YQPPLTTKLS----LSVW-ADFSKPMIEERD------GE---AECVSVGGFPEGRLSWTL 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beat-VII	NP_733162.2	Ig	31..118	CDD:299845	18/102 (18%)
		IG_like	34..118	CDD:214653	17/99 (17%)
		Ig	141..>183	CDD:299845	10/36 (28%)
cd80	XP_031752272.1	Ig	24..118	CDD:416386	21/111 (19%)
		FR1	24..43	CDD:409353	5/20 (25%)
		putative Ig strand A	24..27	CDD:409353	0/2 (0%)
		Ig strand A'	30..33	CDD:409353	1/2 (50%)
		Ig strand B	38..42	CDD:409353	0/3 (0%)
		CDR1	44..50	CDD:409353	2/5 (40%)
		CDR2	72..87	CDD:409353	2/14 (14%)
		Ig strand C'	72..76	CDD:409353	1/3 (33%)
		Ig strand C'	79..82	CDD:409353	0/2 (0%)
		FR3	88..118	CDD:409353	10/45 (22%)
		Ig strand D	91..95	CDD:409353	1/3 (33%)
		Ig strand E	99..103	CDD:409353	0/3 (0%)
		Ig strand F	113..118	CDD:409353	2/4 (50%)
		Ig	<154..217	CDD:416386	5/18 (28%)
		Ig strand C	165..172	CDD:409353	1/7 (14%)
		Ig strand C'	174..176	CDD:409353
		Ig strand D	181..188	CDD:409353
		Ig strand E	192..202	CDD:409353
		Ig strand F	206..215	CDD:409353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1083437at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010