DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TwdlH and TwdlX

DIOPT Version :9

Sequence 1:	NP_651490.1	Gene:	TwdlH / 43208	FlyBaseID:	FBgn0051080	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_728016.1	Gene:	TwdlX / 318094	FlyBaseID:	FBgn0052571	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	79/282 - (28%)
Similarity:	125/282 - (44%)	Gaps:	80/282 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRVLIALCLVAA-----------VSARSGYNYQPAA-----------SAP---AVASFAP--SGP 38
            |:..:.|.::|.           ||..:||:||...           |||   ...|:.|  :|.
  Fly     1 MKQFVVLAVLAVIGGSLAAPRPDVSHLAGYSYQAGGYNGNLVANQVLSAPLTTVTTSYQPTAAGT 65

  Fly    39 SY---SPSV-----AASQDAPAETY----APASAPEAAPSAV------------------ATNYA 73
            :|   :||:     .:|..:....|    :.:|:.:...|:|                  ..||.
  Fly    66 NYYSSAPSIGQLNLGSSGSSGVVNYQVGGSGSSSYQVGSSSVGGGIVNDNIGLAGLQPGPTINYN 130

  Fly    74 APQ-----------AELQKEFFTYTADEQDFVEPAGSQQVSASLN-----KALRVIFIKGPENTG 122
            ..:           |::.|.|:.::|.|..     ..||:...:|     |..||:||..|.:|.
  Fly   131 EQESYISHLANFQPAQINKHFYIHSAPEDH-----DEQQIVRYVNVGRPQKNYRVVFINAPTSTA 190

  Fly   123 LENAAVALAKQAGQQETAIYVLNKQADIGDLSNKLNSIRNNNNNKPEVHFVKYRTNQDALNAQQA 187
            .:...:|..... :::||||||:|:::..|::.::.:.| ...|||||.||||:|.|:|.:|||.
  Fly   191 SKAKIIANVAPV-EEKTAIYVLSKKSNALDVTAEVVTQR-PVANKPEVFFVKYKTPQEAAHAQQT 253

  Fly   188 IQSQYDQLGGSSTILNGGVAPV 209
            ||:.||.|||||...|.||.||
  Fly   254 IQANYDALGGSSETSNEGVIPV 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TwdlH	NP_651490.1	DM5	77..178	CDD:214776	34/105 (32%)
TwdlX	NP_728016.1	DUF243	148..241	CDD:281144	31/99 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000952
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31927
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940