DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment plum and ihog

DIOPT Version :9

Sequence 1:	NP_001163744.1	Gene:	plum / 43197	FlyBaseID:	FBgn0039431	Length:	1298	Species:	Drosophila melanogaster
Sequence 2:	NP_609085.1	Gene:	ihog / 33972	FlyBaseID:	FBgn0031872	Length:	886	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	100/351 - (28%)
Similarity:	144/351 - (41%)	Gaps:	46/351 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LRLPTNEKASGEYYCKIEWDESAVISDRITVEYPVLKRLFPGQQQAA----NISALENKPLVLSC 183
            ||:.......|||.| :.|....|::..|.........|...|:..:    .:||  ...::.||
  Fly   118 LRVLVRPDTLGEYRC-VGWFGPLVVTSTIARLELASTSLVDAQESESPLQWRVSA--GNSVLWSC 179

  Fly   184 --PFLSVPAARFSWYFGNDSLTNDNSALILTNGTLILRHLRLEQAGKYKCVAQNTFASKTHRQF- 245
              ...|.|:|.:|:|.....:..:   .|.|||.|.|.::..|.:|.|.|.|.|. ||....|.
  Fly   180 GQQVQSNPSASWSYYRNGVEIKPE---FIGTNGNLFLSNVSSESSGSYSCQATNP-ASGERIQLP 240

  Fly   246 -IWQLQVEPKDATFYPKNEAGITETAVSEAQLL---PAFQNATVFVPAGGSVLLQCHAVADFVPI 306
             ..||||.|:.     ::|:       ....||   |:.|..|  :..|.|:||.|..|....|.
  Fly   241 GSLQLQVTPEQ-----RSES-------KSPHLLRGQPSSQEIT--IREGSSLLLLCPGVGSPPPT 291

  Fly   307 VWYLQPP-----NNKMVRLSNNSVAYSITNASIARHEGRYSC-----ITPLETQNFQVIVTTPPR 361
            |.:..|.     .||..::..:::..|.|..:.|   |.|.|     :.|......:|.|..||:
  Fly   292 VVWSSPDVVGAVKNKRSKVFGHALEISNTRVNDA---GTYICFQDNGVRPALEHYIKVHVEQPPQ 353

  Fly   362 IVSRLPVEVVYIGLSRTLTCRAEGHPEPSITWYHNGVHLNSSYTRYISGNELHVHSFDSKEEGIY 426
            ||.....::...|....|.|:|.|.|.|.|.|..||..........:|.|.|.:||...:..|..
  Fly   354 IVRPPWADLTNEGDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNNFLILHSVLKRHAGYV 418

  Fly   427 QCVARNVAGEDSATGELRFN-RQLEE 451
            ||.|||..||.||...|:.| :|::|
  Fly   419 QCFARNRLGEHSAGTLLQVNPKQIQE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
plum	NP_001163744.1	IG_like	170..241	CDD:214653	23/72 (32%)
		IGc2	175..235	CDD:197706	18/61 (30%)
		IG_like	284..356	CDD:214653	20/81 (25%)
		I-set	360..443	CDD:254352	29/82 (35%)
		IGc2	378..435	CDD:197706	21/56 (38%)
		FN3	804..886	CDD:238020
ihog	NP_609085.1	IG_like	59..145	CDD:214653	8/27 (30%)
		ig	265..330	CDD:278476	19/69 (28%)
		IG_like	267..348	CDD:214653	21/85 (25%)
		Ig	314..>377	CDD:299845	17/65 (26%)
		IG_like	364..437	CDD:214653	27/72 (38%)
		IGc2	365..427	CDD:197706	22/61 (36%)
		FN3	467..565	CDD:238020
		fn3	580..655	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452282
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840