DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment plum and rst

DIOPT Version :9

Sequence 1:	NP_001163744.1	Gene:	plum / 43197	FlyBaseID:	FBgn0039431	Length:	1298	Species:	Drosophila melanogaster
Sequence 2:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	100/465 - (21%)
Similarity:	160/465 - (34%)	Gaps:	143/465 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VSYRKNDFFIYDNGTLRLPTNEKASG-EYYCKIEWDESAVISDRITVEYPVLK--------RLFP 163
            :.:.|:||        .|.|:...|| |.|..:..||....|..|   |||:.        ::.|
  Fly    58 LQWTKDDF--------GLGTSRDLSGFERYAMVGSDEEGDYSLDI---YPVMLDDDARYQCQVSP 111

  Fly   164 GQQ------------------------QAANISALENKPLVLSCPFLSV---PAARFSWYFGNDS 201
            |.:                        |...|.|.|::.:.:.|  :||   |||..:|..|..:
  Fly   112 GPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIEC--VSVGGKPAAEITWIDGLGN 174

  Fly   202 LTNDN----------SALILTNGTLILRHLRLEQAGKYKCVAQNTFASKTHRQFIWQLQVEPKDA 256
            :..||          .........|.|...:......:.|.|||| |.:|:|..  :::||.|
  Fly   175 VLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNT-ADRTYRSA--KIRVEVK-- 234

  Fly   257 TFYPKNEAGITETAVSEAQLLPAFQNATVFVPAGGS--------------VLLQCHAVAD--FVP 305
             :.||.:..:..:       ||.....:|....|||              |.|:|.|.|:  .|.
  Fly   235 -YAPKVKVNVMGS-------LPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVR 291

  Fly   306 IVWYLQPPNNKMVRLSNNSVAYSITNASIARHEGRYSCITPLETQNF--------QVIVTTPPRI 362
            ..|::   |::.: :........|.|.:...|:....|    |.||.        .:.::..|..
  Fly   292 YRWFI---NDEPI-IGGQKTEMVIRNVTRKFHDAIVKC----EVQNSVGKSEDSETLDISYAPSF 348

  Fly   363 VSRLPVEVVYIGLSRTLTCRAEGHPEPSITWYHN------GVHLNSSYTRYISGNELHVHSFDSK 421
            ..|.......:|...:|||..:.:|:|.|.|..:      |...|.::            |..::
  Fly   349 RQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTF------------SVSNE 401

  Fly   422 EEGIYQCVARNVAG-------------EDSATGELRFNRQLEEVNPLQNIRCY----PHSFHSIN 469
            ..|.|.|.| ||.|             ...|.|..|  .|...|.....|.|:    |.:.| ::
  Fly   402 TAGRYYCKA-NVPGYAEISADAYVYLKGSPAIGSQR--TQYGLVGDTARIECFASSVPRARH-VS 462

  Fly   470 ITFDSRTLTS 479
            .||:.:.::|
  Fly   463 WTFNGQEISS 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
plum	NP_001163744.1	IG_like	170..241	CDD:214653	21/83 (25%)
		IGc2	175..235	CDD:197706	15/72 (21%)
		IG_like	284..356	CDD:214653	19/95 (20%)
		I-set	360..443	CDD:254352	22/101 (22%)
		IGc2	378..435	CDD:197706	16/62 (26%)
		FN3	804..886	CDD:238020
rst	NP_001284835.1	IG_like	34..130	CDD:214653	18/82 (22%)
		Ig	42..114	CDD:299845	18/66 (27%)
		C2-set_2	135..225	CDD:285423	23/92 (25%)
		Ig_3	265..329	CDD:290638	13/71 (18%)
		I-set	346..420	CDD:254352	20/86 (23%)
		Ig	360..425	CDD:299845	18/77 (23%)
		Ig5_KIRREL3-like	428..524	CDD:143235	12/48 (25%)
		IG_like	435..524	CDD:214653	10/41 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11640
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100