Protein Alignment Hex-t2 and EMI2

DIOPT Version :10

• Sequence 1: NP_733151.2
• Gene: Hex-t2 / 43191
• FlyBaseID: FBgn0042710
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_010804.3
• Gene: EMI2 / 852128
• SGDID: S000002924
• Length: 500
• Species: Saccharomyces cerevisiae
• Alignment Length: 528
• Identity: 169/528 - (32%)
• Similarity: 237/528 - (44%)
• Gaps: 122/528 - (23%)

  Fly    38 VNTE-IEAAV----KGFLIDQEKMTEV----VERMTKEI-KMGLAKDTHARAVIKCFVSHVQDLP 92
            ||.| :|.||    ....:|..|:.|:    :|.|.|.: ...:.::......:....::|..||
Yeast     9 VNAEALEDAVVEICSSLQVDAAKLDELTAYFIECMEKGLNNTSVGEEKTVDKGLPMIPTYVTSLP 73

  Fly    93 TGKERGKYLALDLGGSNFRVLLVNLISNSDVETMSKGYNFPQTLMSG---SGKALFDFLAECLSE 154
            .|.|||..||.||||::|||..|.|..:...:........|:..::.   :.:.||.:|......
Yeast    74 NGTERGVLLAADLGGTHFRVCSVTLNGDGTFDMQQLKSKIPEEYLNDKDVTSEELFSYLGRRTRA 138

  Fly   155 FCHSH--------GLENESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAI 211
            |...|        |...:.|.:|||||:|:.|..||.|.|:.|||.|..|..|||:||.|.||.:
Yeast   139 FVRKHHPELLKSTGENIKPLKMGFTFSYPVDQTSLSSGTLIRWTKSFKIEDTVGKDVVRLYQEQL 203

  Fly   212 DRRGDLKINTVAILNDTVGTLMS-CAFYHPNCR-----------IGLIVGTGSNACYVEKTVNAE 264
            |.:|...||.||:.||||||.:| |  |....|           ||.|.|||:|.||:|...|.:
Yeast   204 DIQGLSMINVVALTNDTVGTFLSHC--YTSGSRPSSAGEISEPVIGCIFGTGTNGCYMEDIENIK 266

  Fly   265 ----------CFEGYQTSPKPSMIINCEWGAFGDNGVLEFVRTSYDKAVD-KVTPNPGKQTFEKC 318
                      ..||     |..|.||.|||:| ||.:.....|.||..:| |.:||||...|||.
Yeast   267 KLPDELRTRLLHEG-----KTQMCINIEWGSF-DNELKHLSATKYDIDIDQKFSPNPGYHLFEKR 325

  Fly   319 ISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDVESDAPGEYRN--------- 374
            |||||:|||:|.::.|:.|:|.:.                           |:|||
Yeast   326 ISGMYLGELLRNILVDLHARGLIL---------------------------GQYRNYDQLPHRLK 363

  Fly   375 -----CNKVLSELGI------------------LGCQEPDKEALRYICEAVSSRSAKLCACGLVT 416
                 |::|||.:.|                  |.....:::|::.:..:::.|||.|.|..:..
Yeast   364 TPFQLCSEVLSRIEIDDSTNLRETELSFLQSLRLPTTFEERKAIQNLVRSITRRSAYLAAVPIAA 428

  Fly   417 IINKMNI------NEVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGV----KFELVVSEDGSGRG 471
            |:.|.|.      .||.||.||.|..::|.:..||: |...|...|.    |..|.:::||||.|
Yeast   429 ILIKTNALNKRYHGEVEIGFDGYVIEYYPGFRSMLR-HALALSPIGTEGERKIHLRLAKDGSGVG 492

  Fly   472 AALVAATA 479
            |||.|..|
Yeast   493 AALCALVA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t2	NP_733151.2	ASKHA_NBD_HK_meta	51..477	CDD:466869	161/506 (32%)
EMI2	NP_010804.3	ASKHA_NBD_GLK1-2_fungi	29..497	CDD:466938	160/503 (32%)