Protein Alignment Hex-t2 and YLR446W

DIOPT Version :9

• Sequence 1: NP_733151.2
• Gene: Hex-t2 / 43191
• FlyBaseID: FBgn0042710
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_013551.1
• Gene: YLR446W / 851167
• SGDID: S000004438
• Length: 433
• Species: Saccharomyces cerevisiae
• Alignment Length: 474
• Identity: 105/474 - (22%)
• Similarity: 183/474 - (38%)
• Gaps: 130/474 - (27%)

  Fly    38 VNTEIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKER----G 98
            :.:.:...::..::..:.:..||::..:|:...|..:| ...:.:|.|      |..:.|    .
Yeast     3 IESTLARELESLILPADSIVNVVDQFQEELLSRLQTNT-ISMLPQCLV------PDKRSRWNPED 60

  Fly    99 KYLALDLGGSNFRVLLVNL----ISNSDVETMSKGYNFPQTLMSGSGKALFDFLAECLSEFC--- 156
            |.|.:|.||:..:..:::|    |..:|...::  ||...:          :|..:.:...|
Yeast    61 KILTIDFGGTRLKFAIISLPQIVIEYNDAFELT--YNIVDS----------NFFNQIIYTICTRL 113

  Fly   157 HSHGL---ENES-----LALGFTFSFPLQQQGLSKGILVAWTKGF-SCEGVVGKNVVSLLQEAID 212
            .::|.   :|||     ..:..||||||..:    |.:||..||| ..:.:.|..|..|:|.:..
Yeast   114 AANGYIKKKNESSEASKFFVSVTFSFPLNPE----GEVVAMGKGFVMTDTLQGSTVKQLIQSSFH 174

  Fly   213 RRGDLKI-------NTVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQ 270
            |.....|       |...::||.:...::..|...|..|.||:|||:|||:       |...||.
Yeast   175 RIISENIEEFFCTMNVCHVINDAIAVSLTSKFICENDSISLIIGTGTNACF-------EVPYGYL 232

  Fly   271 TSPKPSMIINCEWGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDM 335
            .             .|..:.:.|.:.:||:|.    |.|     |:..:....:|.:.:.||.
Yeast   233 P-------------PFKRDALRETLPSSYNKE----TLN-----FKHVLINSEIGFIGKNVIA-- 273

  Fly   336 IAKGFMFHGIISEKI------QERW---SFKTAYI--SDVESDAPGEYRNCNKVLSELGILGCQ- 388
             .:.|..||.||.::      ..:|   |.|...:  :.:..:.|.|:.         |.|.||
Yeast   274 -LQPFDIHGAISYEMPLECVTSGKWLPLSLKNILLQYNIIPKNFPVEFN---------GELVCQL 328

  Fly   389 ---------EPDKEALRYICEAVSSRSAKLCACGLVTIINKM-------NINEVAIGIDGS---- 433
                     |.:..||  ||: ::....|..|..:..|:..:       |.|.:.||..||
Yeast   329 AEDCTNAWFENEHYAL--ICQ-IARLLIKRAAFYVAAIVQAIDIITGCKNYNFIHIGYVGSFLHN 390

  Fly   434 --VYRFHPKYHDMLQYHMK 450
              .||...||:..:  |:|
Yeast   391 SNFYREQIKYYSSI--HIK 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t2	NP_733151.2	COG5026	31..483	CDD:227359	105/474 (22%)
		Hexokinase_1	41..237	CDD:278764	46/222 (21%)
		Hexokinase_2	243..477	CDD:281689	57/242 (24%)
YLR446W	NP_013551.1	COG5026	1..433	CDD:227359	105/474 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5026
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910