Protein Alignment Hex-t2 and HXK1

DIOPT Version :10

• Sequence 1: NP_733151.2
• Gene: Hex-t2 / 43191
• FlyBaseID: FBgn0042710
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_116711.3
• Gene: HXK1 / 850614
• SGDID: S000001949
• Length: 485
• Species: Saccharomyces cerevisiae
• Alignment Length: 468
• Identity: 166/468 - (35%)
• Similarity: 246/468 - (52%)
• Gaps: 32/468 - (6%)

  Fly    29 GCNRKMPSLVNTEIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPT 93
            |....:|..:..||......|.:|.|.:.:||:....|:..||.|   ....|......|.:.||
Yeast    14 GSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTK---KGGNIPMIPGWVMEFPT 75

  Fly    94 GKERGKYLALDLGGSNFRVLLVNLISNSDVETMSKGYNFPQTLMSGS-GKALFDFLAECLSEFCH 157
            |||.|.|||:||||:|.||:||.|..|...:|....|..|..:.:.. .:.|:.|:|:.|.:|..
Yeast    76 GKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMV 140

  Fly   158 SHGLEN--ESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKIN 220
            ...|.|  ::|.||||||:|..|..:::|||..|||||....|.|.:||.|||..|.:| :|.|.
Yeast   141 EQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKR-ELPIE 204

  Fly   221 TVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPS---MIINCE 282
            .||::|||||||::..:..|..::|:|.|||.|..:.:...:.|..||......||   |.||||
Yeast   205 IVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCE 269

  Fly   283 WGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIIS 347
            :|:| ||..|...||.||.|||:.:|.||:|.|||..||.|:|||:|||:.::..||.|......
Yeast   270 YGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDL 333

  Fly   348 EKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDKEALRYICEAVSSRSAKLCAC 412
            .|:::.:...|:|.:.:|.|......:.:.:..:...:....|:::.:|.:||.:.:|:|:|..|
Yeast   334 SKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVC 398

  Fly   413 GLVTIINKMNINEVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVK-------------FELVVS 464
            |:..|..|.......|..|||||..:|.:        |:....|::             ..:|.:
Yeast   399 GIAAICQKRGYKTGHIAADGSVYNKYPGF--------KEAAAKGLRDIYGWTGDASKDPITIVPA 455

  Fly   465 EDGSGRGAALVAA 477
            |||||.|||::||
Yeast   456 EDGSGAGAAVIAA 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t2	NP_733151.2	ASKHA_NBD_HK_meta	51..477	CDD:466869	159/444 (36%)
HXK1	NP_116711.3	ASKHA_NBD_HK1-2_fungi	38..471	CDD:466937	160/444 (36%)