Protein Alignment Hex-t2 and GLK1

DIOPT Version :10

• Sequence 1: NP_733151.2
• Gene: Hex-t2 / 43191
• FlyBaseID: FBgn0042710
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_009890.1
• Gene: GLK1 / 850317
• SGDID: S000000545
• Length: 500
• Species: Saccharomyces cerevisiae
• Alignment Length: 482
• Identity: 162/482 - (33%)
• Similarity: 233/482 - (48%)
• Gaps: 57/482 - (11%)

  Fly    49 FLIDQEKMTEVVERMTKEIKMGLA--KDTHARA------VIKCFVSHVQDLPTGKERGKYLALDL 105
            |.:..||:.|:.....::::.|||  |:.|..|      :|..||:   ..|.|.|||..||.||
Yeast    25 FEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVT---GSPNGTERGVLLAADL 86

  Fly   106 GGSNFRVLLVNLISNSDVETMSKGYNFPQTLMSG---SGKALFDFLAECLSEFCHSH-------G 160
            ||:|||:..|||..:............|..|:..   :...||.|||.....|...:       |
Yeast    87 GGTNFRICSVNLHGDHTFSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAKG 151

  Fly   161 LENESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAIL 225
            .:.:.:.||||||:|:.|..|:.|.|:.|||||.....|||:||.|.||.:..:|...|..||:.
Yeast   152 KDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALT 216

  Fly   226 NDTVGTLMSCAFYHPNCR-----------IGLIVGTGSNACYVEKTVN------AECFEGYQTSP 273
            ||||||.:|..:...|..           ||.|.|||:|.||:|: :|      .|..:......
Yeast   217 NDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEE-INKITKLPQELRDKLIKEG 280

  Fly   274 KPSMIINCEWGAFGDNGVLEFVRTSYDKAVD-KVTPNPGKQTFEKCISGMYMGELVRLVITDMIA 337
            |..||||.|||:| ||.:.....|.||..:| |::.|||...|||.:|||::||::|.::.|:.:
Yeast   281 KTHMIINVEWGSF-DNELKHLPTTKYDVVIDQKLSTNPGFHLFEKRVSGMFLGEVLRNILVDLHS 344

  Fly   338 KGFMFHGIISEKIQER-----WSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDKEALRY 397
            :|.:.....|::...|     :...:..:|.:|.|.....|.....|.:...|.....::..::.
Yeast   345 QGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPTTPTERVQIQK 409

  Fly   398 ICEAVSSRSAKLCACGLVTIINKMNI------NEVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPG 456
            :..|:|.|||.|.|..|..|:.|.|.      .||.||.||||..::|.:..||: |...|...|
Yeast   410 LVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLR-HALALSPLG 473

  Fly   457 V----KFELVVSEDGSGRGAALVAATA 479
            .    |..|.:::||||.||||.|..|
Yeast   474 AEGERKVHLKIAKDGSGVGAALCALVA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t2	NP_733151.2	ASKHA_NBD_HK_meta	51..477	CDD:466869	159/476 (33%)
GLK1	NP_009890.1	ASKHA_NBD_GLK1-2_fungi	29..497	CDD:466938	159/473 (34%)