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Protein Alignment Hex-t2 and HKDC1

DIOPT Version :9

Sequence 1:	NP_733151.2	Gene:	Hex-t2 / 43191	FlyBaseID:	FBgn0042710	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_079406.4	Gene:	HKDC1 / 80201	HGNCID:	23302	Length:	917	Species:	Homo sapiens

Alignment Length:	446	Identity:	188/446 - (42%)
Similarity:	282/446 - (63%)	Gaps:	14/446 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDL 105
            :|:..:..|.:.:|::.:|..:|..|::.||.|.:|..|.::...::|..||.|.|:||:|||||
Human   469 QIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDL 533

  Fly   106 GGSNFRVLLVNLIS-NSDVETMSKGYNFPQTLMSGSGKALFDFLAECLSEFCHSHGLENESLALG 169
            ||:|||||||.:.| ...|...:|.:..|..:|.|:|:.|||.:.:|:::|....||:..||.||
Human   534 GGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLG 598

  Fly   170 FTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMS 234
            ||||||.:|..:.||.|:.|||||......|::||.:|:|||.||.:..::.||::||||||:|:
Human   599 FTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMT 663

  Fly   235 CAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPSMIINCEWGAFGDNGVLEFVRTSY 299
            |.:..|||.||||.|||||.||:|...|.|..||    .:..|.||.|||.|||||.::.:.|.|
Human   664 CGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG----GEGKMCINTEWGGFGDNGCIDDIWTRY 724

  Fly   300 DKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDV 364
            |..||:.:.|||||.:||..||||:||:||.::.|:..:|.:|.|.|||:::.|..|:|.::|.:
Human   725 DTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQI 789

  Fly   365 ESDAPGEYRNCNKVLSELGILGCQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNINE---- 425
            |||... .....::|.:||:....| |...::.:|.|||.|:|:||..||..|:.|...::
Human   790 ESDRLA-LLQVRRILQQLGLDSTCE-DSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEH 852

  Fly   426 --VAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVKFELVVSEDGSGRGAALVAATA 479
              :.:|:||::|:.||.:..:||..:|: |.|......::||||||:||||:.|.|
Human   853 LRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVA 907

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.