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Protein Alignment Hex-t2 and Hk2

DIOPT Version :9

Sequence 1:	NP_733151.2	Gene:	Hex-t2 / 43191	FlyBaseID:	FBgn0042710	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_036867.1	Gene:	Hk2 / 25059	RGDID:	2797	Length:	917	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	192/456 - (42%)
Similarity:	291/456 - (63%)	Gaps:	29/456 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 EAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDLGG 107
            :..::...:..|::.||..||..|::.||:|:|||.|.:|...::|...|.|.|:|.:|||||||
  Rat   471 QKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHAVAPVKMLPTYVCATPDGTEKGDFLALDLGG 535

  Fly   108 SNFRVLLVNLISNS--DVETMSKGYNFPQTLMSGSGKALFDFLAECLSEFCHSHGLENESLALGF 170
            :|||||||.:.:..  .||..:|.|:.||.:|.|:|:.|||.:.:|:::|....|::..||.|||
  Rat   536 TNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF 600

  Fly   171 TFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMSC 235
            |||||.||..|.:.||:.|||||...|..|::||:||:|||.||.:..::.||::||||||:|:|
  Rat   601 TFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTC 665

  Fly   236 AFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPSMIINCEWGAFGDNGVLEFVRTSYD 300
            .:..|:|.:||||||||||||:|:..|.|..:|    .:..|.:|.|||||||||.|:.:||.:|
  Rat   666 GYEDPHCEVGLIVGTGSNACYMEEMRNVELVDG----EEGRMCVNMEWGAFGDNGCLDDLRTVFD 726

  Fly   301 KAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDVE 365
            .|||:::.|||||.|||.|||||:||:||.::.|...:|.:|.|.|||:::.|..|:|.::|.:|
  Rat   727 VAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIE 791

  Fly   366 SDAPGEYRNC------NKVLSELGILG-CQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNI 423
            ||       |      ..:|..||:.. |.  |...::.:|..|:.|:|:||..|:..:::|:..
  Rat   792 SD-------CLALLQVRAILRHLGLESTCD--DSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRE 847

  Fly   424 N------EVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVKFELVVSEDGSGRGAALVAATAVQA 482
            |      :|.:|:||::|:.||.:..::...::. |.|......:.||||||:||||:.|.|.:.
  Rat   848 NRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRD-LAPKCDVSFLESEDGSGKGAALITAVACRI 911

  Fly   483 K 483
            :
  Rat   912 R 912

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.