Protein Alignment Hex-t2 and Gck

DIOPT Version :10

• Sequence 1: NP_733151.2
• Gene: Hex-t2 / 43191
• FlyBaseID: FBgn0042710
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001257778.1
• Gene: Gck / 24385
• RGDID: 2670
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 174/401 - (43%)
• Similarity: 265/401 - (66%)
• Gaps: 24/401 - (5%)

  Fly    92 PTGKERGKYLALDLGGSNFRVLLVNL----ISNSDVETMSKGYNFPQTLMSGSGKALFDFLAECL 152
            |.| |.|.:|:|||||:||||:||.:    .....|:|..:.|:.|:..|:|:.:.|||:::||:
  Rat   100 PRG-EVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECI 163

  Fly   153 SEFCHSHGLENESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDL 217
            |:|...|.::::.|.||||||||::.:.|.||||:.|||||...|..|.|:|.||::||.||||.
  Rat   164 SDFLDKHQMKHKKLPLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDF 228

  Fly   218 KINTVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPSMIINCE 282
            :::.||::||||.|::||.:....|.:|:|||||.||||:|:..|.|..||    .:..|.:|.|
  Rat   229 EMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEG----DEGRMCVNTE 289

  Fly   283 WGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIIS 347
            ||||||:|.|:.....||:.||:.:.|||:|.:||.|.|.|||||||||:..::.:..:|||..|
  Rat   290 WGAFGDSGELDEFLLEYDRMVDESSANPGQQLYEKIIGGKYMGELVRLVLLKLVDENLLFHGEAS 354

  Fly   348 EKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEP---DKEALRYICEAVSSRSAKL 409
            |:::.|.:|:|.::|.||||: |:.:..:.:||.||:    .|   |.:.:|..||:||:|:|.:
  Rat   355 EQLRTRGAFETRFVSQVESDS-GDRKQIHNILSTLGL----RPSVTDCDIVRRACESVSTRAAHM 414

  Fly   410 CACGLVTIINKM------NINEVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVKFELVVSEDGS 468
            |:.||..:||:|      ::..:.:|:|||||:.||.:.:.....::: |.|..:...:.||:||
  Rat   415 CSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRR-LTPNCEITFIESEEGS 478

  Fly   469 GRGAALVAATA 479
            |||||||:|.|
  Rat   479 GRGAALVSAVA 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t2	NP_733151.2	ASKHA_NBD_HK_meta	51..477	CDD:466869	172/397 (43%)
Gck	NP_001257778.1	ASKHA_ATPase-like	100..491	CDD:483947	174/401 (43%)