Protein Alignment Hex-t2 and Hk1

DIOPT Version :10

• Sequence 1: NP_733151.2
• Gene: Hex-t2 / 43191
• FlyBaseID: FBgn0042710
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_030100764.1
• Gene: Hk1 / 15275
• MGIID: 96103
• Length: 997
• Species: Mus musculus
• Alignment Length: 452
• Identity: 196/452 - (43%)
• Similarity: 289/452 - (63%)
• Gaps: 17/452 - (3%)

  Fly    41 EIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDL 105
            :||..:..|.:.::.:.||.:::..|::|||.|:|::||.:|...|:|:.:|.|.|.|.:|||||
Mouse   548 QIEETLSHFRLSKQALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIPDGTEHGDFLALDL 612

  Fly   106 GGSNFRVLLVNLISNS--DVETMSKGYNFPQTLMSGSGKALFDFLAECLSEFCHSHGLENESLAL 168
            ||:|||||||.:.|..  .||..:|.|:.|..:|.|:|..|||.:..|:|:|....|::...:.|
Mouse   613 GGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMPL 677

  Fly   169 GFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLM 233
            |||||||.:|..|..|||:.|||||.....||.:|.:||::|:.||.:..::.||::||||||:|
Mouse   678 GFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAVVNDTVGTMM 742

  Fly   234 SCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPSMIINCEWGAFGDNGVLEFVRTS 298
            :||:..|:|.|||||||||||||:|:..|.|..||.|    ..|.||.|||||||||.|:.:||.
Mouse   743 TCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEGNQ----GQMCINMEWGAFGDNGCLDDIRTD 803

  Fly   299 YDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISD 363
            :||.||:.:.|.|||.|||.|||||:||:||.::.|...|||:|.|.|||.::.|..|:|.::|.
Mouse   804 FDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQ 868

  Fly   364 VESDAPGEYRNCNKVLSELGILG-CQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNIN--- 424
            :|||... ......:|.:||:.. |.  |...::.:|..||.|:|:||..|:..::.|:..|
Mouse   869 IESDRLA-LLQVRAILQQLGLNSTCD--DSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGL 930

  Fly   425 ---EVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVKFELVVSEDGSGRGAALVAATAVQAK 483
               .|.:|:||::|:.||.:..::...:|: |.|......::||||||:||||:.|..|:.:
Mouse   931 DHLNVTVGVDGTLYKLHPHFSRIMHQTVKE-LSPKCTVSFLLSEDGSGKGAALITAVGVRLR 991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t2	NP_733151.2	ASKHA_NBD_HK_meta	51..477	CDD:466869	191/434 (44%)
Hk1	XP_030100764.1	ASKHA_ATPase-like	76..553	CDD:483947	2/4 (50%)
		ASKHA_NBD_HK1_meta_rpt2	557..990	CDD:466977	193/440 (44%)