DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Hex-t2 and hkdc1

DIOPT Version :10

Sequence 1:NP_733151.2 Gene:Hex-t2 / 43191 FlyBaseID:FBgn0042710 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_002935347.1 Gene:hkdc1 / 100485269 XenbaseID:XB-GENE-1002857 Length:916 Species:Xenopus tropicalis


Alignment Length:453 Identity:193/453 - (42%)
Similarity:291/453 - (64%) Gaps:20/453 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 EIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDL 105
            |.|..::.|.:..:::.||.:.|.:|:..||.|::|..|.:|...::|:..|.|.|:|.:|||||
 Frog   469 EREKTLEAFSLSTKQLLEVKKIMRQEMDRGLKKESHEEAPVKMLPTYVRSTPDGTEKGDFLALDL 533

  Fly   106 GGSNFRVLLVNLIS-NSDVETMSKGYNFPQTLMSGSGKALFDFLAECLSEFCHSHGLENESLALG 169
            ||:|||||||.:.: ...||..:|.|..||..|.|:|:.|||.:..|:::|....|::..||.||
 Frog   534 GGTNFRVLLVRVRNGRRGVEMHNKIYTIPQDAMVGTGEELFDHIVHCIADFLEYMGMKGVSLPLG 598

  Fly   170 FTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMS 234
            ||||||..|..|::|||:.|||||...|..|::||:||:|||.|..:..::.||::||||||:|:
 Frog   599 FTFSFPCHQNSLNEGILLKWTKGFKATGCEGEDVVNLLKEAIHRHEEFDLDVVAVVNDTVGTMMT 663

  Fly   235 CAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPSMIINCEWGAFGDNGVLEFVRTSY 299
            |.:..|||.:||||||||||||:|:..|.|..||    .:..|.||.||||||||..||..||.:
 Frog   664 CGYEDPNCEMGLIVGTGSNACYMEEMRNVELVEG----EEGRMCINMEWGAFGDNDCLEEFRTVF 724

  Fly   300 DKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDV 364
            |:|||:::.|||||.:||.|||||:||:||.::.|...:|.:|.|.|||:::.|..|:|.::|.:
 Frog   725 DRAVDELSLNPGKQRYEKMISGMYLGEIVRNILIDFTKRGLLFRGKISERLKTRGIFETKFLSQI 789

  Fly   365 ESD--APGEYRNCNKVLSELGILG-CQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNIN-- 424
            |||  |..:.|:   :|..||:.. |.  |...::.:|..|:.|:|:||..|:..:::|:..|  
 Frog   790 ESDRLALLQVRS---ILQHLGLNSTCD--DSIIVKEVCTVVARRAAQLCGAGVAAVVDKIRENRG 849

  Fly   425 ----EVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVKFELVVSEDGSGRGAALVAATAVQAK 483
                :|.:|:||::|:.||.:..::...:.. |.|..:...:.||||||:||||:.|.|.:.:
 Frog   850 LETLKVTVGVDGTLYKLHPHFSSIMHQTVND-LSPKCQVTFLQSEDGSGKGAALITAVACRIR 911

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hex-t2NP_733151.2 ASKHA_NBD_HK_meta 51..477 CDD:466869 188/435 (43%)
hkdc1XP_002935347.1 ASKHA_NBD_HK2_meta_rpt1 30..458 CDD:466975
ASKHA_NBD_HK2_meta_rpt2 479..911 CDD:466978 190/441 (43%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.