DRSC/TRiP Functional Genomics Resources

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Protein Alignment tx and HAND1

DIOPT Version :9

Sequence 1:NP_001287543.1 Gene:tx / 43190 FlyBaseID:FBgn0263118 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_004812.1 Gene:HAND1 / 9421 HGNCID:4807 Length:215 Species:Homo sapiens


Alignment Length:138 Identity:38/138 - (27%)
Similarity:53/138 - (38%) Gaps:38/138 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 RRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRD 159
            |:.:...:||.|...||:||..||.|:|..     .|:|  ||:||.|||||..||..|.|.:..
Human    95 RKGSGPKKERRRTESINSAFAELRECIPNV-----PADT--KLSKIKTLRLATSYIAYLMDVLAK 152

  Fly   160 PSYESEFIGECLEESANREARVDLEANEEAEVELPVPVAKKPAKTKGSGKKSSAASKRQSQKQAK 224
            .:...:                              |.|.|....|..|.:.| ..||:.|:...
Human   153 DAQSGD------------------------------PEAFKAELKKADGGRES-KRKRELQQHEG 186

  Fly   225 IVPQIPPI 232
            ..|.:.|:
Human   187 FPPALGPV 194

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
txNP_001287543.1 HLH 95..154 CDD:278439 25/58 (43%)
HAND1NP_004812.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 53..109 4/13 (31%)
bHLH_TS_HAND1 94..153 CDD:381522 27/64 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 166..198 8/30 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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