DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tx and mespa

DIOPT Version :9

Sequence 1:	NP_001287543.1	Gene:	tx / 43190	FlyBaseID:	FBgn0263118	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001039184.1	Gene:	mespa / 734031	XenbaseID:	XB-GENE-920825	Length:	310	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	54/231 - (23%)
Similarity:	89/231 - (38%)	Gaps:	74/231 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SNEDGESANLADFQLELDPIAEPASKSRKNAPTKSKTKAPPLSK--YR--RKTANARERTRMREI 110
            :||...|.:.|..|:|          ..|:.|..:.||....::  |.  |.:|:.||:.|||.:
Frog    57 ANEAYGSIHTAFTQME----------KLKSKPQDTSTKKDQRNRKVYDRVRNSASEREKMRMRNL 111

  Fly   111 NTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRDPSYESEFIGECLEESA 175
            ::|.:.||..:|.|:     |...:.||||.||||.::||:.|::.:   ..:.|.:.:..||..
Frog   112 SSALQNLRRYLPPAV-----APIGKTLTKIETLRLTIRYISHLSEVL---GLDEETLIKRREEEM 168

  Fly   176 NR--------------------EARVD----------------------LEANEEAEVELPVPVA 198
            .|                    |||..                      |||.|:.        .
Frog   169 RRSNMCHIGLCCCQDRQHNLCSEARPHSSETVNLPYFSSSPRLFPEQNILEAQEQE--------F 225

  Fly   199 KKPAKTKGSGKKSSAASKRQSQKQAKIVPQIPPISS 234
            ::||:....||.|......:|.....:..:  |::|
Frog   226 QQPARWATDGKASDLGDHMKSFSSCALASE--PVNS 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tx	NP_001287543.1	HLH	95..154	CDD:278439	23/60 (38%)
mespa	NP_001039184.1	bHLH_SF	97..160	CDD:381792	25/70 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910