Protein Alignment tx and NEUROG2

DIOPT Version :9

• Sequence 1: NP_001287543.1
• Gene: tx / 43190
• FlyBaseID: FBgn0263118
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_076924.1
• Gene: NEUROG2 / 63973
• HGNCID: 13805
• Length: 272
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 83/303 - (27%)
• Similarity: 112/303 - (36%)
• Gaps: 86/303 - (28%)

  Fly     1 MKSNTYELHNYAD-----------LNDMARATDSKDSRKRKTASARGEKYSLRQKRQKRGSNEDG 54
            :||.|.||....|           |..:...:.|.|..:.:...|.|.  :.||:..:.|....|
Human     3 VKSETLELKEEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGG--ARRQRGAEAGQGARG 65

  Fly    55 ESANLAD-------FQLELDPIAEPA-----SKSRKNAPTKSKTKAPPLSKYRRKTANARERTRM 107
            ..|..|:       ..|..|....|:     |:..|.|.|..:.|     |.||..||.|||.||
Human    66 GVAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIK-----KTRRLKANNRERNRM 125

  Fly   108 REINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRDPSYESEFIGECLE 172
            ..:|.|.:.||..:|..  .|||     |||||.|||.|..||..||:::|       ....|..
Human   126 HNLNAALDALREVLPTF--PEDA-----KLTKIETLRFAHNYIWALTETLR-------LADHCGG 176

  Fly   173 ESANREARVDLEANEEAEVELPVPVAKKPAKTKGSGKKSSAASKRQSQKQAKIVPQIPPISSGES 237
            ........:..||           |...|      |..|:|.|                 |||:|
Human   177 GGGGLPGALFSEA-----------VLLSP------GGASAALS-----------------SSGDS 207

  Fly   238 ---CYATSSIGSPASSAYASLSSSSNSHSSSSSP----GLELD 273
               ....|...|||.|:..| |:|::.:|.:.||    |.::|
Human   208 PSPASTWSCTNSPAPSSSVS-SNSTSPYSCTLSPASPAGSDMD 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tx	NP_001287543.1	HLH	95..154	CDD:278439	28/58 (48%)
NEUROG2	NP_076924.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..69		8/40 (20%)
		bHLH_TS_NGN2_ATOH4	104..172	CDD:381560	34/86 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..264		20/71 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010