DRSC/TRiP Functional Genomics Resources

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Protein Alignment tx and Atoh1

DIOPT Version :9

Sequence 1:NP_001287543.1 Gene:tx / 43190 FlyBaseID:FBgn0263118 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_001102708.1 Gene:Atoh1 / 500156 RGDID:1565171 Length:351 Species:Rattus norvegicus


Alignment Length:290 Identity:75/290 - (25%)
Similarity:110/290 - (37%) Gaps:72/290 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 DSKDSRKRKT------ASARGEKYSLRQKRQKRGSNEDGESANLADFQLELDPIAEPASKSRKNA 80
            ||.|.|...|      .:||..:|.|..  .:.|::|.....:.||.|.||...:.....|:...
  Rat    55 DSTDPRAWLTPTLQGLCTARAAQYLLHS--PELGASEAAAPGDEADGQGELVRRSGCGGLSKSPG 117

  Fly    81 PTK-------------------SKTKAPP------LSKYRRKTANARERTRMREINTAFETLRHC 120
            |.|                   |:.:||.      :.|.||..||||||.||..:|.||:.||:.
  Rat   118 PVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNV 182

  Fly   121 VPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRDPSYESEFIGE--------CLEESANR 177
            :|       :.|.::||:|..||::|..||..|::.::.||     :||        |..:..:.
  Rat   183 IP-------SFNNDKKLSKYETLQMAQIYINALSELLQTPS-----VGEQPPPPAASCKNDHHHL 235

  Fly   178 EARVDLEANEEAEVELPVPVAKKPAKTKGSGKKSS---AASKRQSQKQAKIVPQIPPISSGESCY 239
            .|....|....|.    .....:||  .|.|.:.:   |...|.|          .|.|||....
  Rat   236 RAAASYEGGAGAS----AVAGAQPA--PGGGPRPTPPGACRTRFS----------TPASSGGYSV 284

  Fly   240 ATSSIGSPASSAYASLSSSSNSHSSSSSPG 269
            ...::..||....|..:..:....|.|.||
  Rat   285 QLDALHFPAFEDRALTAMMAQKDLSPSLPG 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
txNP_001287543.1 HLH 95..154 CDD:278439 25/58 (43%)
Atoh1NP_001102708.1 HLH 155..213 CDD:238036 27/64 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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