DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tx and olig2

DIOPT Version :9

Sequence 1:NP_001287543.1 Gene:tx / 43190 FlyBaseID:FBgn0263118 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_835201.1 Gene:olig2 / 325288 ZFINID:ZDB-GENE-030131-4013 Length:273 Species:Danio rerio


Alignment Length:151 Identity:43/151 - (28%)
Similarity:64/151 - (42%) Gaps:23/151 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 DSKDSR-KRKTASARGEKYSLRQKRQKRGSNEDGESANLADFQLELDPIAEPASKSRKNAPTKSK 85
            ||..|| ..:.:|..|:...|...::..|.     |..::..|.:..|....|.....::..:..
Zfish     2 DSDTSRVSSRPSSPEGDDLFLSAVKKSVGF-----SGAVSSTQSDSPPELRGADMRGISSAEEDS 61

  Fly    86 TKAPPLSKYRRK------------TANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLT 138
            .....|||..||            ..|:|||.||.::|.|.:.||..:|.| .|...    .||:
Zfish    62 MALKMLSKKDRKLLSENELQSMRLKINSRERKRMHDLNIAMDGLREVMPYA-HGPSV----RKLS 121

  Fly   139 KITTLRLAMKYITMLTDSIRD 159
            ||.||.||..||.||::|:.:
Zfish   122 KIATLLLARNYILMLSNSLEE 142

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
txNP_001287543.1 HLH 95..154 CDD:278439 26/70 (37%)
olig2NP_835201.1 HLH 88..142 CDD:197674 26/58 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19290
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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