DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tx and ATOH7

DIOPT Version :9

Sequence 1:NP_001287543.1 Gene:tx / 43190 FlyBaseID:FBgn0263118 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_660161.1 Gene:ATOH7 / 220202 HGNCID:13907 Length:152 Species:Homo sapiens


Alignment Length:141 Identity:45/141 - (31%)
Similarity:69/141 - (48%) Gaps:25/141 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 IAEPASKSRKNAPTKSKTKAPPLSKYRRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANT 133
            :|.|.:...:.|.|.:.......:..||..||||||.||:.:||||:.||..||:  .|:|    
Human    15 VAPPCAGGTECAGTCAGAGRLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQ--WGQD---- 73

  Fly   134 NEKLTKITTLRLAMKYITMLTDSIRDP---SYESEFIG-ECLEESANREARVDLEANEEAEVELP 194
             :||:|..||::|:.||..||..:.:.   ..|.:::| .|  |...|:.            .||
Human    74 -KKLSKYETLQMALSYIMALTRILAEAERFGSERDWVGLHC--EHFGRDH------------YLP 123

  Fly   195 VPVAKKPAKTK 205
            .|.||.|.:::
Human   124 FPGAKLPGESE 134

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
txNP_001287543.1 HLH 95..154 CDD:278439 28/58 (48%)
ATOH7NP_660161.1 bHLH_TS_ATOH7 34..102 CDD:381557 30/74 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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