DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tx and Hand2

DIOPT Version :9

Sequence 1:NP_001287543.1 Gene:tx / 43190 FlyBaseID:FBgn0263118 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_034532.3 Gene:Hand2 / 15111 MGIID:103580 Length:217 Species:Mus musculus


Alignment Length:114 Identity:44/114 - (38%)
Similarity:60/114 - (52%) Gaps:13/114 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 RRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIR- 158
            ||.|||.:||.|.:.||:||..||.|:|..     .|:|  ||:||.|||||..||..|.|.:. 
Mouse   100 RRGTANRKERRRTQSINSAFAELRECIPNV-----PADT--KLSKIKTLRLATSYIAYLMDLLAK 157

  Fly   159 -DPSYESEFIGECLEESANREARVDLEANEEAEVELPVPVAKKPAKTKG 206
             |.:.|:|.....::::..:|.:...|.||    .|...|:....||||
Mouse   158 DDQNGEAEAFKAEIKKTDVKEEKRKKELNE----ILKSTVSSNDKKTKG 202

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
txNP_001287543.1 HLH 95..154 CDD:278439 29/58 (50%)
Hand2NP_034532.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 76..116 8/15 (53%)
bHLH_TS_HAND2 100..161 CDD:381477 32/67 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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