Protein Alignment tx and TCF23

DIOPT Version :10

• Sequence 1: NP_524516.2
• Gene: tx / 43190
• FlyBaseID: FBgn0288888
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_786951.1
• Gene: TCF23 / 150921
• HGNCID: 18602
• Length: 214
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 52/250 - (20%)
• Similarity: 88/250 - (35%)
• Gaps: 93/250 - (37%)

  Fly    22 DSKDSRKRKTASARGEKYSLRQKRQKRGSNEDGESANLADFQLELDPIAEPASK-SRKNAPTKSK 85
            |.|.||..:|.....|:.|...:|..|                     |.|..: :|.......:
Human    31 DRKRSRLSRTRQDPWEERSWSNQRWSR---------------------ATPGPRGTRAGGLALGR 74

  Fly    86 TKAPPLSKYRRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYI 150
            ::|.|.:.       ||||:|:|.:..||..|:..:|       |...:.||:|:..|.||..||
Human    75 SEASPENA-------ARERSRVRTLRQAFLALQAALP-------AVPPDTKLSKLDVLVLAASYI 125

  Fly   151 TMLTDSIRDPSYESEFIGECLEESANREARVDLEANEEAEVELP--------------VPVAKKP 201
            ..||.::..                                |||              .|:.|.|
Human   126 AHLTRTLGH--------------------------------ELPGPAWPPFLRGLRYLHPLKKWP 158

  Fly   202 AKTK----GSG----KKSSAASKRQSQKQAKIVPQIPPISSGESCYATSSIGSPA 248
            .:::    |.|    ..::|::..|..:.|::..|:|  ...::..:|:.: |||
Human   159 MRSRLYAGGLGYSDLDSTTASTPSQRTRDAEVGSQVP--GEADALLSTTPL-SPA 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tx	NP_524516.2	bHLH_TS_taxi_Dei	95..157	CDD:381437	21/61 (34%)
TCF23	NP_786951.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..86		16/82 (20%)
		bHLH_SF	78..133	CDD:469605	22/68 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..214		8/39 (21%)