DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ald2 and Aldoc

DIOPT Version :9

Sequence 1:	NP_001247314.1	Gene:	Ald2 / 43189	FlyBaseID:	FBgn0039425	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_036629.1	Gene:	Aldoc / 24191	RGDID:	2091	Length:	363	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	209/353 - (59%)
Similarity:	259/353 - (73%)	Gaps:	3/353 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YP--NKELQEELICISKALVAPGKGILAADESSAVMGKRFQLIGVENTEENRRLYRQMLFTTDPK 69
            ||  :.|.::||..|:..:|||||||||||||...|.||...|||||||||||||||:||:.|.:
  Rat     5 YPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDR 69

  Fly    70 IAENISGVIFYHETLHQRTDDGLPFVEALRKKGILTGIKVDKHFSPLFGSEDEFTTQGLDDLANR 134
            :.:.|.||||:||||:|:.|:|:|||..:::||||.||||||...||.|::.|.||||||.|..|
  Rat    70 VKKCIGGVIFFHETLYQKDDNGVPFVRTIQEKGILVGIKVDKGVVPLAGTDGETTTQGLDGLLER 134

  Fly   135 CAQYKKEGCSFAKWRCILKITKNTPSPQAILENANVMARYAAICQSQRLVPIISPEVLATGDHDL 199
            ||||||:|..||||||:|||:..|||..||||||||:||||:|||...:|||:.||:|..|||||
  Rat   135 CAQYKKDGADFAKWRCVLKISDRTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDL 199

  Fly   200 DRCQKVNEILLAGVYKALSDHHVFLEGTLLQPSMVMPGLQSNKNHPPADIGVATVLAIRRSVPPA 264
            .|||.|.|.:||.||||||||||:||||||:|:||.||......:.|.:|.:|||.|:||:||||
  Rat   200 KRCQFVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPA 264

  Fly   265 VMGVLFCGGAQSEEEATVHLNAINNVPLCKPWAMTFAFDRALQTSILRTWGGKKEQISHAQNELI 329
            |.||.|..|.||||||:::|||||...|.:|||:||::.||||.|.|..|.|:::....|..|.|
  Rat   265 VPGVTFLSGGQSEEEASLNLNAINRCSLPRPWALTFSYGRALQASALSAWRGQRDNAGAATEEFI 329

  Fly   330 KRCRANGLASIGKYVIGSVESSAATERL 357
            ||...||||:.|||. ||.:..||.:.|
  Rat   330 KRAEMNGLAAQGKYE-GSGDGGAAAQSL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ald2	NP_001247314.1	Glycolytic	15..357	CDD:278692	205/341 (60%)
Aldoc	NP_036629.1	Glycolytic	15..363	CDD:395212	206/343 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354209
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3588
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63159
OrthoDB	1	1.010	-	-		D342837at33208
OrthoFinder	1	1.000	-	-		FOG0000633
OrthoInspector	1	1.000	-	-		mtm9110
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11627
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X377
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.820