Protein Alignment Ald2 and ALDOA

DIOPT Version :9

• Sequence 1: NP_001247314.1
• Gene: Ald2 / 43189
• FlyBaseID: FBgn0039425
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001230106.1
• Gene: ALDOA / 226
• HGNCID: 414
• Length: 418
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 206/358 - (57%)
• Similarity: 257/358 - (71%)
• Gaps: 2/358 - (0%)

  Fly     2 TTHFYYP--NKELQEELICISKALVAPGKGILAADESSAVMGKRFQLIGVENTEENRRLYRQMLF 64
            |..:.||  ..|.::||..|:..:|||||||||||||:..:.||.|.||.||||||||.|||:|.
Human    54 TMPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLL 118

  Fly    65 TTDPKIAENISGVIFYHETLHQRTDDGLPFVEALRKKGILTGIKVDKHFSPLFGSEDEFTTQGLD 129
            |.|.::...|.|||.:||||:|:.|||.||.:.::.||.:.||||||...||.|:..|.||||||
Human   119 TADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLD 183

  Fly   130 DLANRCAQYKKEGCSFAKWRCILKITKNTPSPQAILENANVMARYAAICQSQRLVPIISPEVLAT 194
            .|:.|||||||:|..||||||:|||.::|||..||:|||||:||||:|||...:|||:.||:|..
Human   184 GLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPD 248

  Fly   195 GDHDLDRCQKVNEILLAGVYKALSDHHVFLEGTLLQPSMVMPGLQSNKNHPPADIGVATVLAIRR 259
            |||||.|||.|.|.:||.|||||||||::||||||:|:||.||....:.....:|.:|||.|:||
Human   249 GDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRR 313

  Fly   260 SVPPAVMGVLFCGGAQSEEEATVHLNAINNVPLCKPWAMTFAFDRALQTSILRTWGGKKEQISHA 324
            :|||||.|:.|..|.||||||:::|||||..||.||||:||::.||||.|.|:.||||||.:..|
Human   314 TVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAA 378

  Fly   325 QNELIKRCRANGLASIGKYVIGSVESSAATERL 357
            |.|.:||..||.||..|||.......:||:|.|
Human   379 QEEYVKRALANSLACQGKYTPSGQAGAAASESL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ald2	NP_001247314.1	Glycolytic	15..357	CDD:278692	201/341 (59%)
ALDOA	NP_001230106.1	Glycolytic	69..418	CDD:306729	202/343 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160141
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2120
OMA	1	1.010	-	-		QHG63159
OrthoDB	1	1.010	-	-		D342837at33208
OrthoFinder	1	1.000	-	-		FOG0000633
OrthoInspector	1	1.000	-	-		mtm8632
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X377
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.910