DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk15 and ppk10

DIOPT Version :9

Sequence 1:	NP_001097937.1	Gene:	ppk15 / 43188	FlyBaseID:	FBgn0039424	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_001033894.1	Gene:	ppk10 / 3885617	FlyBaseID:	FBgn0065110	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	121/502 - (24%)
Similarity:	202/502 - (40%)	Gaps:	92/502 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 YCTNCTLAGFAYIANSRLHFMERIFWLICVFMSSLGCYQLIMGYQRSFPTRAVSIVYESLPPFSK 91
            |..||.:.||.|:.:|.|...|:..|||.:..|...|..:.:.....:.|::..|..|....|..
  Fly    22 YFNNCCIHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLSSIDRYYTKSTHIGIERNYIFWN 86

  Fly    92 WKFPAVSVCELAYRGNLFPKFEEYITSLGV-----DVTGDYPYDVETGVSILLFPALYNEN---- 147
            ...|:|:||.:. |.|: ..|.:|..:.|:     |:..|:..::.....|.......||.
  Fly    87 TTLPSVTVCPVD-RLNI-TYFADYCRNNGIKGPQRDILWDFLENLANSTYINFQNIPQNEQIDQI 149

  Fly   148 ----GLKGKCGT-VHKNCTDACAKCPSDNYRQILTWYGANCSD--LFVECKLSHEPFDCCRHFLP 205
                |||.:..| :..|.|......|:.|.|       ..|.|  :|:             |...
  Fly   150 IEDIGLKPEHYTELIYNLTYDRTYEPNFNER-------IRCMDGAMFI-------------HVRQ 194

  Fly   206 LLTPFGRCYMLNSLLNNEPGSKHWLPNELDPAHQKAVINVITRLDVQISVINAEDIPHTAFFPPG 270
            :||.:|.||:.||.|..|..|::::..:....::....|:  ||..|:.....:|..:......|
  Fly   195 VLTEWGLCYLGNSKLTEEYSSRYFIFGKYPEYNKYEYENI--RLPYQVGSFFQKDTQYALLGFKG 257

  Fly   271 IPLIT-------------------EGLSKYMQFNQVAMKNDPDVKDIDPKIRSCFFPEEIPADSL 316
            ..:|.                   :|:...:...::..:::.: :|....:|.|.||.|   .:|
  Fly   258 PAIIAFAHSAFEVMKVDSNSDYAYDGILYDLSTEEITAEDNLE-QDTTVAMRRCRFPHE---SNL 318

  Fly   317 --YKSYSFSVCITECIRRLQMKACNCTSFLYNPN--ADPRYPDCDLEG-----------FLCLEK 366
              :..|:.::|..||...|..|.|.|....| ||  |:|: |.||.:.           ||.|.:
  Fly   319 THFPFYTRNICQQECRINLAYKICKCIPHFY-PNRIANPK-PVCDYKTLRSCFPHHASFFLKLYE 381

  Fly   367 TRMIKPDSRVLVNNNKGNNASCGCLPSCNDGDIT-TIYEPLLFVRNPNKYYNGTLDMPFLPTDQY 430
            .           |....|.|.|.|..:|:|..:| ....|:...:.........:.:...|..:.
  Fly   382 E-----------NGKHENPAICYCEQNCHDSVVTMKSMNPMSGAKQLLGGIGSAVSVKTWPQSRL 435

  Fly   431 RRQSLRTPLDVVVSMGGMLGLFLGASILSAIEFVYYFTVRPLSNMLG 477
            |||.:.:..|::||:||..|||||.|:|..:|.:|:||:|.:..:||
  Fly   436 RRQVIFSLTDLLVSIGGTAGLFLGFSVLGFVEVIYFFTIRIVFQILG 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:279230	115/489 (24%)
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	115/489 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920