Protein Alignment ppk15 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001097937.1
• Gene: ppk15 / 43188
• FlyBaseID: FBgn0039424
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 125/595 - (21%)
• Similarity: 201/595 - (33%)
• Gaps: 190/595 - (31%)

  Fly    27 YCTNCTLAGFAYIANSRLHFMERIFWLI---CVFMSSLGCYQLIMGYQRSFPTRAVSIVYESLPP 88
            :|.|.|:.|...:..|:.:.|:..||.:   |.|......:.|:.....|:|. :::|...|
  Rat    88 FCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYLSYPV-SLNINLNS--- 148

  Fly    89 FSKWKFPAVSVCEL-AYR----------------GNLFPKFE---EYITSLGV------DVTGDY 127
             .|..||||:||.| .||                ..||..::   .|....|.      |:.|.:
  Rat   149 -DKLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLGAF 212

  Fly   128 PYDVETGVSILLFPALYNENGLKGKCGTVHKN---------------CTDACAKCPSDNYRQ--- 174
            |:.::   .:...|..|:....:....:|..|               |....:.|....|..
  Rat   213 PHPLQ---RLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVD 274

  Fly   175 -ILTWYG-------ANCSD------------LFVECKLSHEP-----FDCCRHFLPLLTPFGRCY 214
             :..||.       :..||            ....|:.:..|     :....|  |:   :|.||
  Rat   275 AVREWYRFHYINILSRLSDTSPALEEEALGNFIFTCRFNQAPCNQANYSKFHH--PM---YGNCY 334

  Fly   215 MLNSLLNNE------PGSKHWL-------PNELDPAHQKAVINVITRLDVQISVINAEDIPHTAF 266
            ..|...|:.      ||..:.|       .|:..|     :::.:|...|   :::.:|.|  ||
  Rat   335 TFNDKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIP-----LLSTVTGARV---MVHGQDEP--AF 389

  Fly   267 FPPGIPLITEGLSKYMQFNQVAM-----------KNDPDVKDIDPKIRSCFFPEEIPADSLYKS- 319
            ...|...:..|:...:...:.|:           :|..||                |..:||.|
  Rat   390 MDDGGFNLRPGVETSISMRKEALDSLGGNYGDCTENGSDV----------------PVKNLYPSK 438

  Fly   320 YSFSVCITECIRRLQMKACNCTSFLYNPNADPRYPD-CD-------------------LEGFLCL 364
            |:..|||..|.:...:|.|.| ::::.|.  |:..: ||                   |:...|.
  Rat   439 YTQQVCIHSCFQENMIKKCGC-AYIFYPK--PKGVEFCDYRKQSSWGYCYYKLQGAFSLDSLGCF 500

  Fly   365 EKTRMIKPDSRVLVNNNKGNNASCGCLPSCNDGDITTIYEPLLFVRN--PNKYYNGTLDMP-FLP 426
            .|.|  ||.|.:    |...:|.....||....|  .|:|.|....|  .|...||...:. |..
  Rat   501 SKCR--KPCSVI----NYKLSAGYSRWPSVKSQD--WIFEMLSLQNNYTINNKRNGVAKLNIFFK 557

  Fly   427 TDQYRRQSLRTPLDVVVS----MGGMLGLFLGASILSAI---EFVYYFTVRPLSNML-------- 476
            ...|:..| .:|...:||    :|....|:.|:|:||.:   |.::...|..|..:|
  Rat   558 ELNYKTNS-ESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLLMLLRRFRSRYW 621

  Fly   477 ----GARAAR 482
                |||.||
  Rat   622 SPGRGARGAR 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:279230	117/565 (21%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	125/595 (21%)
		deg-1	88..600	CDD:273309	116/562 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820