DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk15 and ppk3

DIOPT Version :9

Sequence 1:	NP_001097937.1	Gene:	ppk15 / 43188	FlyBaseID:	FBgn0039424	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_726336.1	Gene:	ppk3 / 246504	FlyBaseID:	FBgn0050181	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	112/483 - (23%)
Similarity:	189/483 - (39%)	Gaps:	101/483 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LAGFAYIANSRLHFMERIFWLICVFMSSLGCYQLI-MGYQRSFPTRAVSIVYESLPPFSKW--KF 94
            |...:...|..:|.:||:|||..|..|.:....|. :..:|.|.:..|..|...   :..|  ..
  Fly    52 LLALSLCVNRSIHLLERLFWLAVVVSSVIAALVLSRLQLERYFSSPTVISVDRD---YRGWNGSL 113

  Fly    95 PAVSVCELAYRGNLFPKFEEYITSL-GVDVTG-DYPYDVETGVSILLFPALYNENGLKGKCGTVH 157
            |||::|...:..:.  |..|||..: .|.:.. ||.|.::...:::        |...|....:.
  Fly   114 PAVTLCYYDHIDSF--KANEYIQEMWNVSIIDEDYFYFMDFLYAVV--------NATAGNYAELA 168

  Fly   158 KNCTDACAKCPSDNYRQILTWYGANCSDLFVECKLSHEPFDCC---------RHFLPLLTPFGRC 213
            |...|       :.:.||         ||:...:....||:..         .|...::|..|.|
  Fly   169 KFAED-------ERFDQI---------DLYEMIQRVDRPFEQVISSFDAGFQVHVQRVMTERGAC 217

  Fly   214 YMLNS----LLNNEPGSKHWLPNELDPAHQK-------------AVINVITRLDVQISVINAEDI 261
            |.:||    :|:.:|.:...:|..|...:.|             .|::|.:..:|..:..|...:
  Fly   218 YAINSPMSTVLSGQPVAYELMPQPLSCQYGKQQCYIRMDLYESTGVLDVHSPFEVSATEANIVAL 282

  Fly   262 PHTAFFPPGIPLITEGLSKYMQFNQVAMKNDPDVKDIDPKIRSCFFPEEIPADSLYKSYSFSVCI 326
             |.:         .|..:.:.....||.||   ::.:....|.|.|..|  ..|..|.||.|:|:
  Fly   283 -HKS---------DEITASFKVLETVASKN---LRQLSVAQRKCVFNNE--ETSNLKIYSKSLCL 332

  Fly   327 TECIRRLQMKACNCTSFLYNPNADPRYPDCDLEGFLCLEKTRMIKPDSRVLVNNNKGNNASCGCL 391
            ..|...:.::.|||..|.| |..|.  |.|:..||.||...:.  |...:.:         |.|.
  Fly   333 ARCRAVMALEMCNCVPFFY-PYVDG--PSCNPAGFECLLDFKW--PIWALHI---------CKCP 383

  Fly   392 PSCNDGDIT--TIYEPLLFVRNPNKYYNG-TLDMPFL-----PTDQYRRQSLRTPLDVVVSMGGM 448
            .:|.:.:.|  |:.:....|:|..:..:. |....|.     |..:.||..:.:..|:|||.||:
  Fly   384 STCTEIEYTMQTVKKSSWGVKNNEEVASSETATSSFRWDLIPPKVRMRRDVVYSFEDLVVSFGGV 448

  Fly   449 LGLFLGASILSAIEFVYYFTVRPLSNML 476
            |.||:|.|::..:|.|:..    ::|:|
  Fly   449 LALFVGVSVMGLVEMVHVL----VNNLL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:279230	110/471 (23%)
ppk3	NP_726336.1	ASC	59..464	CDD:279230	108/462 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920