Protein Alignment ppk15 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001097937.1
• Gene: ppk15 / 43188
• FlyBaseID: FBgn0039424
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 596
• Identity: 127/596 - (21%)
• Similarity: 202/596 - (33%)
• Gaps: 192/596 - (32%)

  Fly    27 YCTNCTLAGFAYIANSRLHFMERIFWLI---CVFMSSLGCYQLIMGYQRSFPTRAVSIVYESLPP 88
            :|.|.|:.|...:..|:.:.|:..||.:   |.|......:.|:.....|:|. :::|...|
Mouse    88 FCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYFSYPV-SLNINLNS--- 148

  Fly    89 FSKWKFPAVSVCEL-AYR----------------GNLFPKFE---EYITSLG------VDVTGDY 127
             .|..||||:||.| .||                ..||..::   .|....|      .|:.|..
Mouse   149 -DKLVFPAVTVCTLNPYRYTEIKEDLEELDRITEQTLFDLYKYNSSYTRQAGGRRRSTRDLRGAL 212

  Fly   128 PYDVETGVSILLFPALYN-ENGLKGKCGTVHKN---------------CTDACAKCPSDNYRQ-- 174
            |:.::.    |..|...| ....:....:|..|               |....:.|....|..
Mouse   213 PHPLQR----LRTPPPPNPARSARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGV 273

  Fly   175 --ILTWYGANCSDL------------------FV-ECKLSHEP-----FDCCRHFLPLLTPFGRC 213
              :..||..:..::                  |: .|:.:..|     :....|  |:   :|.|
Mouse   274 DAVREWYRFHYINILSRLPDTSPALEEEALGSFIFTCRFNQAPCNQANYSQFHH--PM---YGNC 333

  Fly   214 YMLNSLLNNE------PGSKHWL-------PNELDPAHQKAVINVITRLDVQISVINAEDIPHTA 265
            |..|:..|:.      ||..:.|       .|:..|     :::.:|...|   :::.:|.|  |
Mouse   334 YTFNNKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIP-----LLSTVTGARV---MVHGQDEP--A 388

  Fly   266 FFPPGIPLITEGLSKYMQFNQVAM-----------KNDPDVKDIDPKIRSCFFPEEIPADSLYKS 319
            |...|...:..|:...:...:.|:           :|..||                |..:||.|
Mouse   389 FMDDGGFNVRPGVETSISMRKEALDSLGGNYGDCTENGSDV----------------PVKNLYPS 437

  Fly   320 -YSFSVCITECIRRLQMKACNCTSFLYNPNADPRYPD-CD-------------------LEGFLC 363
             |:..|||..|.:...:|.|.| ::::.|.  |:..: ||                   |:...|
Mouse   438 KYTQQVCIHSCFQENMIKKCGC-AYIFYPK--PKGVEFCDYLKQSSWGYCYYKLQAAFSLDSLGC 499

  Fly   364 LEKTRMIKPDSRVLVNNNKGNNASCGCLPSCNDGDITTIYEPLLFVRN--PNKYYNGTLDMP-FL 425
            ..|.|  ||.|   |.|.| .:|.....||....|  .|:|.|....|  .|...||...:. |.
Mouse   500 FSKCR--KPCS---VTNYK-LSAGYSRWPSVKSQD--WIFEMLSLQNNYTINNKRNGVAKLNIFF 556

  Fly   426 PTDQYRRQSLRTPLDVVVS----MGGMLGLFLGASILSAIE---------------FVYYFTVRP 471
            ....|:..| .:|...:||    :|....|:.|:|:||.:|               .::.|..|.
Mouse   557 KELNYKTNS-ESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLIMLLHRFRSRY 620

  Fly   472 LSNMLGARAAR 482
            .|...|||.||
Mouse   621 WSPGRGARGAR 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:279230	119/578 (21%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	127/596 (21%)
		deg-1	88..600	CDD:273309	119/563 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820