Protein Alignment ppk15 and asic-2

DIOPT Version :10

• Sequence 1: NP_001097937.1
• Gene: ppk15 / 43188
• FlyBaseID: FBgn0039424
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 120/546 - (21%)
• Similarity: 191/546 - (34%)
• Gaps: 176/546 - (32%)

  Fly    16 RGFGFVTNIKDYCTNCTLAGFAYIANSRLHFMERIFWLICVFMSSLG--CYQLIMGYQRSFPTRA 78
            ||.|||...||:....|:|...::||:. :.:.|||| |.:|:..||  .|:|.:...:.|...|
 Worm     2 RGGGFVQIFKDFSNWSTVAVVPHVANAN-NKISRIFW-IAIFLFVLGMFAYELYILIAKFFSYPA 64

  Fly    79 VSIVYESLPPFSKWKFPAVSVCEL-AYR------GNLFPKFEEYITSL-------------GVDV 123
             ::..|.|  |.|..||.|:||.: .|:      .:.|......:|:.             |:..
 Worm    65 -TVNTEIL--FEKQIFPVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYA 126

  Fly   124 TGDYPYDVETGVSILLFPALYNENGLKGKCGTVHKNCTDACAKCPSDNYRQILTWYGANCSDLFV 188
            ..|..||:::..:..|               .:..|.....||.|:     :.|:     :||..
 Worm   127 DNDETYDLDSRAADAL---------------VLEANLISDTAKVPA-----LYTY-----ADLIQ 166

  Fly   189 ECKLSHEPFDCCR-HFLPLLTP-FGRCYMLNSLLNNEPGSKHWLPNELDPAHQKAVINV-ITRLD 250
            :|..:..|  |.. .|...:.| :|.||..|                     :.|.:|. ::|..
 Worm   167 DCSFAGIP--CSESDFTKFIDPVYGACYSFN---------------------EDASLNYSVSREG 208

  Fly   251 VQISVI------------NAEDIPHTAFFPPGIPLITEGLSKYMQFN----------QVAMKNDP 293
            :|..:.            |.:.:|.|......|.:.:.|.|..:..|          .|::....
 Worm   209 IQFGLKLMLTVTQTKTNGNTDSLPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQ 273

  Fly   294 DVKDIDPKIRSCFFPEEIPADSLYKS--YSFSVCITECIRRLQMKACNCTSFLYNPNADPRYPDC 356
            :|:...| ..:|...|...:| .||.  |:...|...|.:|..:..|.|        |:||
 Worm   274 NVRAKKP-YGTCVDREPDSSD-YYKDFIYTLETCFNGCKQRDTIAKCQC--------ANPR---- 324

  Fly   357 DLEGFLCLEKT----RMIKPDSRVLVNNNKGNNAS----------CGCLPSCNDGDITTIYEPLL 407
                 |.|..|    :.||.|...| ...|||..|          |.|.|.|::    :.|.|.:
 Worm   325 -----LALGSTDTACQPIKADLDCL-QTLKGNQTSSTPNIDLLVECNCNPPCDE----STYTPTV 379

  Fly   408 FVRN--PNKYY-------------------------------NGTLDMPFLPT---DQYRRQSLR 436
            .:..  ...||                               ||.:...||.|   :.|...:..
 Worm   380 SLAQFPSTSYYVATSSTAGVGSCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGY 444

  Fly   437 TPLDVVVSMGGMLGLFLGASILSAIE 462
            |..:|:..:||..||:||.|::|.:|
 Worm   445 TVSNVINDLGGQAGLWLGLSVISVVE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:459966	113/535 (21%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	114/536 (21%)