DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk15 and del-10

DIOPT Version :9

Sequence 1:	NP_001097937.1	Gene:	ppk15 / 43188	FlyBaseID:	FBgn0039424	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	381	Identity:	80/381 - (20%)
Similarity:	135/381 - (35%)	Gaps:	103/381 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VFMSSLGCYQLIMGYQRSFPTRAVSIVYESLPPFSKWKFPAVSVC-----ELAY--RGNLFPKFE 113
            |.:..:.||..|    :.:.:..|:...|:..| ||..||.|::|     .|.|  .|.:..:..
Worm   105 VILVLVQCYSQI----KLYISEPVATNIEAEYP-SKISFPTVAICNNNQFRLTYLTGGRIMNRRS 164

  Fly   114 EYITSLGVDVTGDYPYDVETGVSILLFPALYNENGLKGKCGTVHKNCTDACAKCPSDNYRQIL-- 176
            :.|:. .:..||   :|||:....:|..: ::.:.:|......|...            |.||
Worm   165 KSISG-SLLSTG---HDVESVFDTVLRKS-WDMDAVKFLRSAAHWKS------------RMILGC 212

  Fly   177 TWYGANCSDLFVECKLSHEPFDCCRHFLPLLTPFGRCYMLNSLLNNE-----PGSKHWLPNELDP 236
            ||...      ..||||        .|..:.|..|.|:.:|:..:|.     .|..|.|
Worm   213 TWPNG------TSCKLS--------DFKAVWTTTGLCWAINTDPHNPYEVTGSGEGHGL------ 257

  Fly   237 AHQKAVINV--ITRLD-------------VQISVINAEDIPHTAFFPPGIPLITEGLSKYMQFNQ 286
               :.::||  ..|:|             ::|.:.|..|||.::.....:|   .|.|..:.|..
Worm   258 ---RLLLNVESYERVDACTKHFRTKTLPGLKILIYNQTDIPDSSMNGVNVP---SGYSMDIPFKM 316

  Fly   287 VAMKNDPDVKDIDPKIRSCFFPEEIPADSLYKSYSFSVCITECIRRLQM----KACNCT-SFLYN 346
            ........|..|:..      .|:|.|.:   .::....|..|..|..|    .:|:|| ...|.
Worm   317 QHRSKLTGVHCIEEN------DEQIEAST---DFNNPENIRTCTLRRYMTEVENSCHCTLRRAYT 372

  Fly   347 PNA-DPRYPDCDLEGFL-CLEKTRMIKPDSRVLVNNNKGNNASCGCLPSCNDGDIT 400
            .|: |.:...|:::.:. |.:|.          :...:....:..|||.|...|.|
Worm   373 SNSTDVKMKACNVDQYFGCAQKA----------MQRIREEGTASTCLPPCKSIDYT 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:279230	80/381 (21%)
del-10	NP_495302.3	ASC	83..>419	CDD:279230	80/381 (21%)
del-10	NP_495302.3	ASC	<789..849	CDD:279230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820