Protein Alignment ppk15 and Asic3

DIOPT Version :10

• Sequence 1: NP_001097937.1
• Gene: ppk15 / 43188
• FlyBaseID: FBgn0039424
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 563
• Identity: 116/563 - (20%)
• Similarity: 199/563 - (35%)
• Gaps: 169/563 - (30%)

  Fly    22 TNIKDYCTNCTLAGFAYIANSRLHFMERIFWLICVFMS-SLGCYQLI--MGYQRSFPTRAVSIVY 83
            ::|:.:..:||:.|..:|.......:.|..|...|.:| :...||:.  :.|...|..:......
Mouse    16 SDIRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDER 80

  Fly    84 ESLPPFSKWKFPAVSVCELAYRGNLFPKFEEYITSLGVDVTGDYPYDVE-TGVSIL-LFPALYNE 146
            ||    .:..||||::|      |:.|.....:|          |.|:. .|.::| |.||
Mouse    81 ES----HQLTFPAVTLC------NINPLRRSRLT----------PNDLHWAGTALLGLDPA---- 121

  Fly   147 NGLKGKCGTVHKNCTDACAK---------CPSDNYRQILTWYGANCSDLFVECKLSHEPFDCC-- 200
                     .|.....|..:         .|:.:..|:....|.:..|:.::|:...:|   |
Mouse   122 ---------EHAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQP---CGP 174

  Fly   201 RHFLPLLTPFGRCYMLNS-------LLNNEPGSKHWLPNELDPAHQ------KAVINVITRLDVQ 252
            .:|..:.|..|:||..||       |...:.|:.:.|...||...:      |.:......:.::
Mouse   175 ENFTVIFTRMGQCYTFNSGAQGAELLTTPKGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIR 239

  Fly   253 ISVINAEDIPHTAFFPPGIPLI----TEGLSKYMQFNQVAMK------NDPDVKDIDPKIRSCFF 307
            :.:...|:       ||.|..:    ..|...::...|..:.      .|.:...:||.    |.
Mouse   240 VQIHGQEE-------PPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASVDPD----FD 293

  Fly   308 PEEIPADSL-----YKSYSFSVCITECIRRLQMKACNCTSFLYNPNADP-----RYPDC------ 356
            ||  |:|.|     ...||...|...|..|...:.|.| ..::.|...|     :|.||
Mouse   294 PE--PSDPLGSPSSSPPYSLIGCRLACESRYVARKCGC-RMMHMPGNSPVCSPQQYKDCASPALG 355

  Fly   357 -------------DLEG--------FLCLEKT-RMIKPDSRVLVNNNKGNNASCGCLPSCNDGDI 399
                         |::.        ||.|... .|::.|             :|.|...|    .
Mouse   356 KAHLFSLPVPIHSDIDHNPLGQVLLFLALRPADAMLRKD-------------TCVCPNPC----A 403

  Fly   400 TTIY-EPLLFVRNPN--------KYYNGT----------LDMPF--LPTDQYRRQSLRTPLDVVV 443
            ||.| :.|..||.|:        :.||.:          ||:.|  |..:...:::.....:::.
Mouse   404 TTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLG 468

  Fly   444 SMGGMLGLFLGASILSAIEFVYY----FTVRPLSNMLGARAAR 482
            .:||.:|||:|||:|:.:|.:.|    |..|.|......|:::
Mouse   469 DIGGQMGLFIGASLLTILEILDYLCEVFQDRVLGYFWNRRSSQ 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk15	NP_001097937.1	ASC	27..466	CDD:459966	110/536 (21%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	115/558 (21%)