DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33970 and ABCB5

DIOPT Version :9

Sequence 1:	NP_001034071.1	Gene:	CG33970 / 43186	FlyBaseID:	FBgn0053970	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_192092.1	Gene:	ABCB5 / 826974	AraportID:	AT4G01830	Length:	1230	Species:	Arabidopsis thaliana

Alignment Length:	334	Identity:	86/334 - (25%)
Similarity:	139/334 - (41%)	Gaps:	78/334 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 VLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEI-------------WVLGGRPGS 117
            |..|.::.:|.|:...|:|.||.||:|::|.|......|||::             |:.|
plant   370 VFGGFSLLIPSGTTTALVGESGSGKSTVISLIERFYDPNSGQVLIDGVDLKEFQLKWIRG----- 429

  Fly   118 RGSGVPGPRIGYMPQEIALYGEFTMRETLIYFG-------IISAMSKGDIEDRTEFLLKLLNLPN 175
                    :||.:.||..|:....|..  |.:|       .|.|.||               |.|
plant   430 --------KIGLVSQEPVLFSSSIMEN--IGYGKEGATVEEIQAASK---------------LAN 469

  Fly   176 ASKFV---------------KNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHL 225
            |:||:               ..|||||::|:::|.|:|.:|.:|:|||.|..:|....:.:.:.|
plant   470 AAKFIDKLPLGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEAL 534

  Fly   226 VDITKNGHTTVIITTHYIDECAQAHMIGLLRGGKMLAEESPDYLRQQYNADSLEDVFLKLSVLQN 290
            ..|..| .||||: .|.:.....|.:|.::..||::.|.|...|.:.:     |..:.:|..||.
plant   535 DRIMVN-RTTVIV-AHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDH-----EGAYSQLLRLQE 592

  Fly   291 MGKR-RRSSIAQEIVEQVTVPAISNPALDMSDEQHAAEISGEFGDNISMSSAARDPISTTAPAAP 354
            :.|. :|..|:...:...:....::...|.........::|:  |:..||......:|.|..||.
plant   593 INKESKRLEISDGSISSGSSRGNNSTRQDDDSFSVLGLLAGQ--DSTKMSQELSQKVSFTRIAAL 655

  Fly   355 PLPPPQEIP 363
            ..|   |||
plant   656 NKP---EIP 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	65/238 (27%)
		CcmA	54..321	CDD:224054	74/290 (26%)
		ABC2_membrane_3	394..770	CDD:289468
		ABC2_membrane	<581..738	CDD:279410
ABCB5	NP_192092.1	PTZ00265	2..1224	CDD:240339	86/334 (26%)
		ABC_membrane	35..293	CDD:279056
		ABC_MTABC3_MDL1_MDL2	353..591	CDD:213216	68/257 (26%)
		ABC_membrane	667..936	CDD:279056
		ABC_MTABC3_MDL1_MDL2	985..1224	CDD:213216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000