Protein Alignment CG33970 and Abca2

DIOPT Version :9

• Sequence 1: NP_001034071.1
• Gene: CG33970 / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_006233707.2
• Gene: Abca2 / 79248
• RGDID: 620238
• Length: 2435
• Species: Rattus norvegicus
• Alignment Length: 1038
• Identity: 201/1038 - (19%)
• Similarity: 353/1038 - (34%)
• Gaps: 342/1038 - (32%)

  Fly    10 PTAPAATATTANSDLDLAARRRLF------ISQPSTLATRRQQAVCVRRAHKMYGSSKNPNVVLD 68
            |.|.|...:....|...|...|.|      ..:|:.|..    .|||.:..|:|.:.|  .:.|:
  Rat   951 PWAHAPRLSVMEEDQACAMESRHFEETRGMEEEPTHLPL----VVCVDKLTKVYKNDK--KLALN 1009

  Fly    69 GLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRGSGVPGPRIGYMPQE 133
            .|::.:.:..:...||.:|.||||.:|.:.|.....||...:.|....:....: ...:|..||.
  Rat  1010 KLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEI-RKNLGMCPQH 1073

  Fly   134 IALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNLPN-ASKFVKNLSGGQQRRVSLAVAL 197
            ..|:.:.|:.|.|.::..:.:|::.:|....:.:::.|.|.| ....|:.||||.:|::|:|:|.
  Rat  1074 NVLFDQLTVEEHLWFYSRLKSMAQEEIRKEMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAF 1138

  Fly   198 LHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTHYIDECAQAHMIG----LLRGG 258
            :.....:||||||.||||..|::||| |:...|.|. |::::||::||   |.::|    ::..|
  Rat  1139 VGGSRAIILDEPTAGVDPYARRAIWD-LILKYKPGR-TILLSTHHMDE---ADLLGDRIAIISHG 1198

  Fly   259 KMLAEESPDYLRQQYN------------------------------------------------- 274
            |:....||.:|:..|.
  Rat  1199 KLKCCGSPLFLKGAYGDGYRLTLVKRPAEPGTSQEPGMASSPSGRPQLSNCSEMQVSQFIRKHVA 1263

  Fly   275 -----AD-------------------------------------------SLEDVFLKLS----V 287
                 :|                                           :||:||||:|    .
  Rat  1264 SSLLVSDTSTELSYILPSEAVKKGAFERLFQQLEHSLDALHLSSFGLMDTTLEEVFLKVSEEDQS 1328

  Fly   288 LQNM--------------------------GKRRRSSIAQEIVEQVTVPAISNPALDMSDEQHAA 326
            |:|.                          ...|.|.:||   .|.::.:.|:......||  .|
  Rat  1329 LENSEADVKESRKDALPGAEGLTAVESQAGNLARCSELAQ---SQASLQSASSVGSARGDE--GA 1388

  Fly   327 EISGEFG------------DNISMSSAARDPISTTAPAAPPLPPPQEIPTSFWYNLHVMQSHHLH 379
            ..:..:|            |::|:..|..:.::.....:..|       ..:|     ::....|
  Rat  1389 GYTDGYGDYRPLFDNLQDPDSVSLQEAEMEALARVGQGSRKL-------EGWW-----LKMRQFH 1441

  Fly   380 ALIWKNFLWMMRNVGVMLFIVGLP------VVQILLFCYAIG------------HD---PTGLKL 423
            .|:.|.|....||...:...:.||      .:.:.|....||            |:   |.|..:
  Rat  1442 GLLVKRFHCARRNSKALCSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFI 1506

  Fly   424 AVANHE-----------MSGEMIMEQF---------CPVHTGCNQT---MLSCRYLDMLVKNKSM 465
            ..||.|           .|.:.::..|         |.:.:..|.:   ||:      |...:|.
  Rat  1507 PYANEERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPANGSLGPMLN------LSSGESR 1565

  Fly   466 VVQYVTDDEMAYEEVRKGRAWAALVIQPNYTA---SLMERVEDGRYAEDGTIESSDLAVRMDWSN 527
            ::.....|.|..|...:|...:..|..|...|   |.:...||...|.:.::..:.......|:
  Rat  1566 LLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPLSPDEDSLLAWNTSLPPTAGPETWTWA- 1629

  Fly   528 QQISQLLYRDL------QYTFFN--------------FVGDMLSDC---DVNPKL---------- 559
            ..:.:|::..:      |.|.|:              ..||:|:|.   :|:..|
  Rat  1630 PSLPRLVHEPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLH 1694

  Fly   560 -------GRVPVDFQHPVYGYRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLERCLV 617
                   |.:......|: |.|.|              :....:||...|.::..|:|.......
  Rat  1695 RYGAITFGNIQKSIPAPI-GTRTP--------------LMVRKIAVRRVAQVLYNNKGYHSMPTY 1744

  Fly   618 AGITGPEILLSQV-----------VTQFTVMLSQTTFVLIVSFYFFELTLVGNIWLVVALCILNG 671
            .......||.:.:           :|.....:::|:..|.:.:......:|..|:::||
  Rat  1745 LNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVA------ 1803

  Fly   672 LCGMSF---GFVISCAVDTERTATYVAMGSFL-PIV-MLCGIIWP-IEGMFP----LLQFFTAFL 726
               |||   .||:....:....|.::...|.. |:: .|...:|. :..:.|    ::..|...|
  Rat  1804 ---MSFVPASFVVFLVAEKSTKAKHLQFVSGCNPVIYWLANYVWDMLNYLVPATCCIIILFVFDL 1865

  Fly   727 P-LTKPTE---SMRSILQRGWGIDNPVVY-------------------NGFISISSWVLVFLV 766
            | .|.||.   .:...|..||.| .|::|                   |.||.|::.|..||:
  Rat  1866 PAYTSPTNFPAVLSLFLLYGWSI-TPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLL 1927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	69/226 (31%)
		CcmA	54..321	CDD:224054	84/398 (21%)
		ABC2_membrane_3	394..770	CDD:289468	90/504 (18%)
		ABC2_membrane	<581..738	CDD:279410	31/181 (17%)
Abca2	XP_006233707.2	rim_protein	1..2369	CDD:130324	201/1038 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810