Protein Alignment CG33970 and abcg2a

DIOPT Version :9

• Sequence 1: NP_001034071.1
• Gene: CG33970 / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: XP_021325521.1
• Gene: abcg2a / 735312
• ZFINID: ZDB-GENE-050517-35
• Length: 644
• Species: Danio rerio
• Alignment Length: 782
• Identity: 147/782 - (18%)
• Similarity: 274/782 - (35%)
• Gaps: 250/782 - (31%)

  Fly    55 KMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLN--SGEIWVLGGRPGS 117
            |...:.||   :|.||| .:.|..:..:|||:|.||::.|..:..|:...  |||:.:
Zfish    50 KSKSTKKN---ILIGLN-GIMKPGLNAILGATGSGKSSFLDVLAARKDPAGLSGEVLI------- 103

  Fly   118 RGSGVPGP-----RIGYMPQEIALYGEFTMRETLIYFGII---SAMSKGDIEDRTEFLLKLLNLP 174
              .|.|.|     ..||:.|:..:.|..|:||.|.:...:   .::.:.:.:::.|.|::.|.|.
Zfish   104 --DGAPQPPNFKCLSGYVVQDDVVMGTLTVRENLRFSAALRLPKSIKQREKDEKVERLIQELGLS 166

  Fly   175 N------ASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGH 233
            .      .::.::.:|||:::|.::.:.|:.:|.:|.|||||.|:|.....|:...|..:..||.
Zfish   167 KVADSRVGTQLIRGVSGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLMLLKKMGNNGR 231

  Fly   234 TTVIITTH--------YIDECAQAHMIGLLRGGKML----AEESPDYLRQ------QYN--ADSL 278
             |:|::.|        ..|.      :.||.|||::    |:::..|..|      .:|  ||..
Zfish   232 -TIILSIHQPRYSIYRLFDS------LTLLVGGKLVYHGPAQDALSYFSQIGYTCEPHNNPADFF 289

  Fly   279 EDVFLKLSVLQNMGKRRRSSIAQEIVEQVTVPAISNPALD-MSDEQHAAEISGEFGDNISMSSAA 342
            .||....|....:.|     :.:|:|:|..:.:......| :.:|...:.|..:...::......
Zfish   290 LDVINGDSSAVTLNK-----LYEEVVDQDQLSSSLKGIEDRLVEEYQRSSIFQQTHADLQRIVQG 349

  Fly   343 RDPISTTAPAAPPLPPPQEIPTSFWYNLHVMQSHHLHALIWKNFLWMMRN-------VGVMLFIV 400
            :|  .:|.|.:..:    ...|||        .|..|.::.:.|..:|.|       :|||:|
Zfish   350 QD--YSTRPKSRTI----TYSTSF--------CHQFHWVLKRTFRNLMLNPQTSVAQIGVMIF-- 398

  Fly   401 GLPVVQILLFCYAIGHDPTGLKLAVANHEMSGEMIMEQFCPVHTGCNQTMLSCRYLDMLVKNKSM 465
             |.:|...:| :.:..:.:|::     :.|.....:.        .||...|....::.:..:.:
Zfish   399 -LALVVGAIF-FGVAENSSGIQ-----NRMGALFFIT--------TNQCFSSVSAAELFIAERKL 448

  Fly   466 VV-QYVTDDEMAYEEVRKGRAWAALVIQPNYTASLMERVEDGRYAEDGTIESSDLAVRMDWSNQQ 529
            .| :|::.
Zfish   449 FVHEYISG--------------------------------------------------------- 456

  Fly   530 ISQLLYRDLQYTFFNFVGDMLSDCDVNPKLGRVP-VDFQHPVYGYRNPNFTDFAAPGVILTIIFF 593
                .||...|.....:.|:|:       |..:| |.|....|      |.....|......||.
Zfish   457 ----YYRVSVYFLSKILSDILT-------LRTIPAVIFSCVAY------FMIGLKPAAEAFFIFL 504

  Fly   594 LAVAVTSGAMLIDRNEGMLERCLVAGITGPEILLSQVVTQFTVMLSQTTFVLIVSFYFFELTLVG 658
            .::                            |::|...|..|:.:|....|:.::..|..::.
Zfish   505 FSI----------------------------IMVSYTATAMTLAISADQTVVAIANIFMTISF-- 539

  Fly   659 NIWLVVALCILNGLCGMSFGFVISCAVDTERTATYVAMGSFLPIVMLCGIIWPIEGMFPL-LQFF 722
                 |.:.|.:||           .|:....||::....:..|        |..|:..| :..|
Zfish   540 -----VFMMIFSGL-----------LVNLPSVATWLNWLKYFSI--------PRYGLSALQINEF 580

  Fly   723 TAFLPLTKPTESMRSILQRG-------------WGIDNPVVYNGFISISSWVLVFLVLTILLLKF 774
            |..........| .|:...|             ||:     :...:::.....:||.:..|.|:|
Zfish   581 TGLFFCDNRNNS-GSVCSSGEEFLQEQGIDYSAWGL-----WQNHLALGIMTFIFLCIAYLKLRF 639

  Fly   775 KK 776
            .|
Zfish   640 IK 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	63/242 (26%)
		CcmA	54..321	CDD:224054	75/302 (25%)
		ABC2_membrane_3	394..770	CDD:289468	55/391 (14%)
		ABC2_membrane	<581..738	CDD:279410	24/157 (15%)
abcg2a	XP_021325521.1	PRK10535	43..638	CDD:333000	144/777 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000