Protein Alignment CG33970 and abca4

DIOPT Version :9

• Sequence 1: NP_001034071.1
• Gene: CG33970 / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_001011033.1
• Gene: abca4 / 496442
• XenbaseID: XB-GENE-1000810
• Length: 2359
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 142/596 - (23%)
• Similarity: 258/596 - (43%)
• Gaps: 115/596 - (19%)

  Fly    55 KMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRG 119
            |:|.::..|.|  |.:|:|..:|.|...||.:|.||||.||.|.|.....||.:||.|....:..
 Frog  1004 KVYENTYKPAV--DRMNITFYEGQITAFLGHNGAGKTTTLSIITGLFPPTSGTVWVRGRDIQTHM 1066

  Fly   120 SGVPGPRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNLPN-ASKFVKNL 183
            ..: ...:|..||...|:...|:.|.::::..:...|:...|.:.|.:|:.:.:|: .:...:||
 Frog  1067 DSI-RQSLGMCPQHNILFRHLTVEEHILFYAQLKGKSRKQAERQAEVMLEDMGIPHKRNDEAQNL 1130

  Fly   184 SGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTHYIDECAQ 248
            |||.||::|:|:|.:.|.::::|||||.||||..|:||||.|:.. ::|. |:|::||::||
 Frog  1131 SGGMQRKLSVALAFVGESKVVVLDEPTSGVDPYSRRSIWDLLLKY-RSGR-TIILSTHHMDE--- 1190

  Fly   249 AHMIG----LLRGGKMLAEESPDYLRQQYNADSLEDVFLKLSVLQNMGKRRRSSIAQEIVEQVT- 308
            |.::|    ::..||:....||.:|:..:.......:..::..:::.||:..:|...:.....:
 Frog  1191 ADLLGDRIAIVSQGKLFCSGSPLFLKNCFGTGFYLTLVRRMRNIKDTGKKDSASCQSDCSCPCSS 1255

  Fly   309 -VPAISNPALDMSDEQHAAEISGEFGDNISMSSAARDPISTTAPAAPPLPP-PQEIPTSFWYNLH 371
             .|.:....|:.       |:.|:.       |...:.|....|.|..|.. .||:       ::
 Frog  1256 CTPKVKENLLEQ-------ELDGDV-------SGLTELIHHHVPEAKLLESIGQEL-------IY 1299

  Fly   372 VMQS----HHLHALIWKNFLWMMRNVGVMLF-IVGLPVVQILLFCYAIGHDPTGLKLAVANHEMS 431
            ::.|    ...:|.:::.....:.::|:..| |...|:.:|.|...|.         :|...|..
 Frog  1300 LLPSKDFKFRAYASLFRELEETLGDLGLSSFGISDTPLEEIFLKVTAD---------SVTGTETP 1355

  Fly   432 GEMIMEQFCPVHTGCNQTMLSCRYLDMLVKNKSMVVQYVTDDEMAYEEVRKGRAWAALVIQPNYT 496
            .|.:::|      ..::|.|.       |.|::.|:.  .|::.....:||..........|
 Frog  1356 EEWMLQQ------RKSRTSLG-------VDNQTTVIN--IDNKGQESSIRKDSHHCKAEKNP--- 1402

  Fly   497 ASLMERVEDGRYAEDGTIESSDLAVRMDWSNQQISQLLYRDLQYT------FF-------NFVGD 548
            .::.:|..|||.:..  |:.::|.      .||.:.|:.:..::.      ||       :||..
 Frog  1403 PNINDREADGRGSRQ--IKGTELL------QQQFNALIIKRFKHATRSHKDFFAQIVLPASFVLL 1459

  Fly   549 MLSDCDVNPKLGRVPVDFQHP-VYGYRNPNFTDFAAPGVILTIIFFL-------AVAVTSGAMLI 605
            .|....:.|..|..|....|| :||.:               .:||.       .:|..|.|.|
 Frog  1460 ALVFTLIVPPFGEYPSLTLHPWIYGQQ---------------FVFFSNEQPGNEQMATFSNAFL- 1508

  Fly   606 DRNEGMLERCL 616
             .:.|:..||:
 Frog  1509 -NSPGLGTRCM 1518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	75/219 (34%)
		CcmA	54..321	CDD:224054	81/272 (30%)
		ABC2_membrane_3	394..770	CDD:289468	50/245 (20%)
		ABC2_membrane	<581..738	CDD:279410	9/43 (21%)
abca4	NP_001011033.1	rim_protein	1..2347	CDD:130324	142/596 (24%)
		ABC2_membrane	604..>778	CDD:304374
		ABC_subfamily_A	997..1216	CDD:213230	75/219 (34%)
		ABC_subfamily_A	2013..2233	CDD:213230

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910