Protein Alignment CG33970 and Abcg4

DIOPT Version :9

• Sequence 1: NP_001034071.1
• Gene: CG33970 / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_001100286.2
• Gene: Abcg4 / 300664
• RGDID: 1305840
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 845
• Identity: 147/845 - (17%)
• Similarity: 270/845 - (31%)
• Gaps: 298/845 - (35%)

  Fly     3 AAADGVPPTAPAATATTANSDLDLAARRRLFISQPSTLATRRQQAVCVRRAHKMYGSSKNP---- 63
            |..||..|  |..|......:..:...:| |...|      ::.||.:......|...:.|
  Rat    23 ALEDGAEP--PVLTTHLKKVENHITEAQR-FSHLP------KRSAVDIEFVELSYSVREGPCWRK 78

  Fly    64 ---NVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLN-SGEIWVLGGRPGSRGSGVPG 124
               ..:|..|:....:..:.|::|.||.||:|.::.:.|.|... .|:| ::.|||  |......
  Rat    79 RGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQI-LVNGRP--RDLRTFR 140

  Fly   125 PRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDR--TEFLLKLLNLPNASKFVKNLSGGQ 187
            ....|:.|:..|....|:.|.::....:....|.:::..  ||.|..|..:..:......|||||
  Rat   141 KMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQ 205

  Fly   188 QRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITK---NGHTTVIITTHYIDECAQA 249
            ::|:::|:.|::.|.::..||||.|:|    .:....:|.:.|   :|..|||.|.|
  Rat   206 RKRLAIALELVNNPPVMFFDEPTSGLD----SASCFQVVSLMKSLAHGGRTVICTIH-------- 258

  Fly   250 HMIGLLRGGKMLAEESPDYLRQQYNADSLEDVFLKLSVLQNMGKRRRSSIAQEIVEQVT-----V 309
                                  |.:| .|.::|.||.:| :.|:.....:...::..:.     .
  Rat   259 ----------------------QPSA-KLFEMFDKLYIL-SQGQCIFKGVVTNLIPYLKGLGLHC 299

  Fly   310 PAISNPALDMSDEQHAAEI-SGEFGD-NISMSSAARDPISTTA-----------PAAPPLPPPQE 361
            |...|||      ....|: |||:|| |..:..|.::.:.|.|           ||..|..||:
  Rat   300 PTYHNPA------DFIIEVASGEYGDLNPMLFRAVQNGLCTMAEKKSSPEKNEVPAHCPTCPPE- 357

  Fly   362 IPTSFWYNLHVMQSHHLHALIWKNFLWMMRNVGVMLFIVGLPVVQILLFCYAIGHDPTGLKLAVA 426
                    |..::||.........|..:.|..    |:             :|..|.....|...
  Rat   358 --------LDPIESHTFATSTLTQFCILFRRT----FL-------------SILRDTVLTHLRFM 397

  Fly   427 NHEMSGEMIMEQFCPVHTGCNQTMLSCRYLDMLVKNKSMVVQYVTDDEMAYEEVRKGRAWAALVI 491
            :|.:.|.:|                            .::..::.||
  Rat   398 SHVLIGVLI----------------------------GLLYLHIGDD------------------ 416

  Fly   492 QPNYTASLMERVEDGRYAEDGTIESSDLAVRMDWSNQQISQLLYRDLQYTFFNFVGDMLSDCDVN 556
                                                   :..::.:..:.||:.:  .|....:.
  Rat   417 ---------------------------------------ASKVFNNTGFLFFSML--FLMFAALM 440

  Fly   557 PKLGRVPVDF-----QHPVYGYRNPNFTDFAAPGVILTIIFFLAVAVTSGAMLIDRNEGMLERCL 616
            |.:...|::.     :|..|.|.              ...::||..:..               :
  Rat   441 PTVLTFPLEMAVFMREHLNYWYS--------------LKAYYLAKTMAD---------------V 476

  Fly   617 VAGITGPEILLSQVVTQFTVMLSQTTFVLIVSFYFFELTLVGNIWLVVALCILNGLCGMSFGFVI 681
            ...:..|.:..| :|...|...::|:..|:.|                ||.|...|...|.|.:|
  Rat   477 PFQVVCPVVYCS-IVYWMTGQPAETSRFLLFS----------------ALSIATALVAQSLGLLI 524

  Fly   682 SCAVDTERTATYVAMGSFLPIVMLCGIIWPIEGMFPLLQFFTAF--LPLTKPTESMRSILQRGW- 743
            ..|..:.:.||:|...:.:|:::..|             ||.:|  :|......|..|.::.|:
  Rat   525 GAASTSLQVATFVGPVTAIPVLLFSG-------------FFVSFKTIPTYLQWSSYLSYVRYGFE 576

  Fly   744 ---------------------------------GIDNPVVYNGFISISSWVLVFLVLTILLLKFK 775
                                             .::...:|..|:.:..:.|...:|..|:|:::
  Rat   577 GLILTIYGMERGHLTCLEDHCPFRDPQIILHELDVEEAKLYMDFLVLGIFFLALRLLAYLVLRYR 641

  Fly   776  775
              Rat   642  641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	53/234 (23%)
		CcmA	54..321	CDD:224054	64/284 (23%)
		ABC2_membrane_3	394..770	CDD:289468	50/416 (12%)
		ABC2_membrane	<581..738	CDD:279410	27/158 (17%)
Abcg4	NP_001100286.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000