Protein Alignment CG33970 and ABCA1

DIOPT Version :9

• Sequence 1: NP_001034071.1
• Gene: CG33970 / 43186
• FlyBaseID: FBgn0053970
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_005493.2
• Gene: ABCA1 / 19
• HGNCID: 29
• Length: 2261
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 84/337 - (24%)
• Similarity: 152/337 - (45%)
• Gaps: 73/337 - (21%)

  Fly    50 VRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGR 114
            ::...|:|...:.|.|  |.:.:.:|.|..:||||.:|.||::....:.|...:..|:.::
Human  1914 IKELTKIYRRKRKPAV--DRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFL---- 1972

  Fly   115 PGSRGSGVPG-----PRIGYMPQEIALYGEFTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNLP 174
              ::.|.:..     ..:||.||..|:....|.||.:.:|.::..:.:.::....|:.::.|.|.
Human  1973 --NKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLV 2035

  Fly   175 N-ASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVII 238
            . ..|:..|.|||.:|::|.|:||:..|.::.|||||.|:||..|:.:|:..:.:.|.|. :|::
Human  2036 KYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGR-SVVL 2099

  Fly   239 TTHYIDEC-------------------AQAHM---------------------------IGLLRG 257
            |:|.::||                   :..|:                           .||...
Human  2100 TSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQDFFGLAFP 2164

  Fly   258 GKMLAEESPDYLRQQY--NADSLEDVFLKLSVLQNMGKR---RRSSIAQEIVEQVTVPAISNPAL 317
            |.:|.|:..:.|:.|.  :..||..:|   |:|....||   ...|::|..::||.|    |.|.
Human  2165 GSVLKEKHRNMLQYQLPSSLSSLARIF---SILSQSKKRLHIEDYSVSQTTLDQVFV----NFAK 2222

  Fly   318 DMSDEQHAAEIS 329
            |.||:.|..::|
Human  2223 DQSDDDHLKDLS 2234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	63/271 (23%)
		CcmA	54..321	CDD:224054	80/323 (25%)
		ABC2_membrane_3	394..770	CDD:289468
		ABC2_membrane	<581..738	CDD:279410
ABCA1	NP_005493.2	rim_protein	6..2236	CDD:130324	84/337 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1283..1312

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810