DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33970 and abt-4

DIOPT Version :9

Sequence 1:	NP_001034071.1	Gene:	CG33970 / 43186	FlyBaseID:	FBgn0053970	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_503175.1	Gene:	abt-4 / 178559	WormBaseID:	WBGene00000022	Length:	1802	Species:	Caenorhabditis elegans

Alignment Length:	332	Identity:	95/332 - (28%)
Similarity:	159/332 - (47%)	Gaps:	30/332 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DLDLAARRRLFISQPSTLATRRQQAVCVRRAHKMYGSSKNPNVVLDGLNMTVPKGSIYGLLGASG 87
            |.|:.|.:    |....||...:.|:......|.||   |.|.| .|:|..|.....:||||.:|
Worm  1429 DSDVIAEK----SVVQRLANNNKTALVSNNLVKWYG---NFNAV-KGVNFHVNSKDCFGLLGVNG 1485

  Fly    88 CGKTTLLSCIVGRRRLNSGEIWVLGGRPGSRGSGVPGPRIGYMPQEIALYGEFTMRETLIYFGII 152
            .|||:....:.|...::||:.:|.|....:..... |...||.||..|:..|.:..|||..|..|
Worm  1486 AGKTSTFQMLTGENSISSGDAYVNGWSVKNNWREA-GANTGYCPQYDAIIKEMSGEETLYMFARI 1549

  Fly   153 SAMSKGDIEDRTEFLLKLLNL-PNASKFVKNLSGGQQRRVSLAVALLHEPELLILDEPTVGVDPV 216
            ..:.:.||..:...::..:.: ..||:.:|..|||.:||:||.:|::..|::|:|||||.||||.
Worm  1550 RGIPEKDIPKKVNAVIHAIGIGMYASRQIKTYSGGNKRRLSLGIAIVGLPDVLLLDEPTSGVDPK 1614

  Fly   217 LRQSIWDHLVDITKNGHTTVIITTHYIDEC-AQAHMIGLLRGGKMLAEESPDYLRQQYNADSLED 280
            .|:.||:.|..:...| |.:::|:|.:||| |....:.::..||.....|..:::.:|.:.....
Worm  1615 ARRIIWNILNRLRDLG-TALVLTSHSMDECEALCTELAIMVYGKFRCYGSCQHIKSRYGSGYTLL 1678

  Fly   281 VFLKLSVLQNMGKRRRSSIAQEIVEQVTVPAISNPALDMSDEQHAAEISGEF---GDNISMSSAA 342
            :.||   .:|..::.:|:|.|.....|.            .|:|..:::.:.   ||:.|.....
Worm  1679 IRLK---NRNDAEKTKSTIKQTFRGSVI------------KEEHVLQLNFDIPRDGDSWSRLFEK 1728

  Fly   343 RDPISTT 349
            .:.:||:
Worm  1729 LETVSTS 1735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	73/223 (33%)
		CcmA	54..321	CDD:224054	81/268 (30%)
		ABC2_membrane_3	394..770	CDD:289468
		ABC2_membrane	<581..738	CDD:279410
abt-4	NP_503175.1	ABC2_membrane_3	<281..523	CDD:289468
		NosY	<377..524	CDD:224196
		CcmA	581..905	CDD:224054
		ABC_subfamily_A	586..815	CDD:213230
		ABC2_membrane_3	<1078..1318	CDD:289468
		ABC_subfamily_A	1450..1668	CDD:213230	73/223 (33%)
		drrA	1457..1755	CDD:130256	88/300 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810