DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33970 and wht-1

DIOPT Version :9

Sequence 1:	NP_001034071.1	Gene:	CG33970 / 43186	FlyBaseID:	FBgn0053970	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_001348731.1	Gene:	wht-1 / 175859	WormBaseID:	WBGene00015479	Length:	671	Species:	Caenorhabditis elegans

Alignment Length:	431	Identity:	98/431 - (22%)
Similarity:	163/431 - (37%)	Gaps:	125/431 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 MYGSSKN-------PNVVLDGLNMTVPK----------------GSIYGLLGASGCGKTTLLSCI 97
            :|.||.|       |...:|.....:||                |.:..:||:||.|||||::.:
Worm    49 LYWSSLNVTGPETKPTNFVDRFRNNMPKRRVKEILHNVSGMAESGKLLAILGSSGAGKTTLMNVL 113

  Fly    98 VGRRRLN---SGEIWVLGGRPGSRGSGVPGPRI----GYMPQEIALYGEFTMRETLIYFGIISAM 155
            ..|...|   .|.| ::.||..::.      :|    .::.|.....|..|.||.|.:   ::.:
Worm   114 TSRNLTNLDVQGSI-LIDGRRANKW------KIREMSAFVQQHDMFVGTMTAREHLQF---MARL 168

  Fly   156 SKGD-----------IED-RTEFLLK-----LLNLPNASKFVKNLSGGQQRRVSLAVALLHEPEL 203
            ..||           :|. .|:..||     ::.:||.   :|.||.|:::|:|.|..:|..|::
Worm   169 RMGDQYYSDHERQLRVEQVLTQMGLKKCADTVIGIPNQ---LKGLSCGEKKRLSFASEILTCPKI 230

  Fly   204 LILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTHYIDECAQAHMIGLLRGGKMLAEESPDY 268
            |..||||.|:|..:...:...|..:..|| .|||||.|.    ..:|:..|.....::|.....|
Worm   231 LFCDEPTSGLDAFMAGHVVQALRSLADNG-MTVIITIHQ----PSSHVYSLFNNVCLMACGRVIY 290

  Fly   269 LRQQYNADSLEDVFLKLSVLQNMGKRRRSSIAQEIVEQVTVPAISNPA------LDMSDEQHAAE 327
            |..   .|....:|.|..                    ...||..|||      |.:.|...|..
Worm   291 LGP---GDQAVPLFEKCG--------------------YPCPAYYNPADHLIRTLAVIDSDRATS 332

  Fly   328 -----------ISGEFGDNI-------SMSSAARDPISTTAPAAPPLPPPQEIPTSFWYNLHVMQ 374
                       :|.:.|.::       .:.:|:....|.|:...... ..|:...|||
Worm   333 MKTISKIRQGFLSTDLGQSVLAIGNANKLRAASFVTGSDTSEKTKTF-FNQDYNASFW------- 389

  Fly   375 SHHLHALIWKNFLWMMRNVGVMLFIVGLPVVQILLFCYAIG 415
             ....||.|:::|.::|:..    ::.:.::|||:..:..|
Worm   390 -TQFLALFWRSWLTVIRDPN----LLSVRLLQILITAFITG 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	68/260 (26%)
		CcmA	54..321	CDD:224054	78/317 (25%)
		ABC2_membrane_3	394..770	CDD:289468	4/22 (18%)
		ABC2_membrane	<581..738	CDD:279410
wht-1	NP_001348731.1	3a01204	76..667	CDD:273361	91/404 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000