DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33970 and abca10

DIOPT Version :9

Sequence 1:	NP_001034071.1	Gene:	CG33970 / 43186	FlyBaseID:	FBgn0053970	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	XP_031750511.1	Gene:	abca10 / 100485734	XenbaseID:	XB-GENE-6464279	Length:	1610	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	93/372 - (25%)
Similarity:	155/372 - (41%)	Gaps:	75/372 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SDLD---LAARRRLFISQPSTLATRRQQAVCV----RRAHKMY--GS--SKNPNVVLDGLNMTVP 75
            :|:|   ||.:.|  :.:.:|:|...::.|.:    |:.:|:.  ||  .||.......::..|.
Frog  1243 NDVDEDVLAEKER--VKKAATIANVEEKPVIIADSLRKEYKVKKGGSFFKKNKRAATKNVSFCVK 1305

  Fly    76 KGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLGGRP-GSRGSGVPGPRIGYMPQEIALYGE 139
            ||.:.||||.:|.||||.:..:.|..:..:||:.:.|..| ||.|.      :||.||:..|:..
Frog  1306 KGEVLGLLGPNGAGKTTSMYMLAGEVKPTAGEVLLCGNDPVGSTGF------LGYCPQDNPLWPN 1364

  Fly   140 FTMRETLIYFGIISAMSKGDIEDRTEFLLKLLNL-PNASKFVKNLSGGQQRRVSLAVALLHEPEL 203
            .|::|.|..:..:..|.|.|.......:...|.| .:..|..:.||.|..|:|..|:::|..|.:
Frog  1365 LTVKEHLEIYAAVKGMKKEDASIAINRVASALELKEHMGKAARKLSLGVSRKVCFAISMLGNPNI 1429

  Fly   204 LILDEPTVGVDPVLRQSIWDHLVDITKNGHTTVIITTHYIDEC-AQAHMIGLLRGGKMLAEESPD 267
            ::||||:.|:||..:|.:|..:....||.....|:||||::|. |....:.::..||:....|..
Frog  1430 VLLDEPSTGLDPKGQQRLWRAIRAAFKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQ 1494

  Fly   268 YLRQQY-----------------------------------------------NADSLEDVFLKL 285
            .|:.::                                               |..||...||.|
Frog  1495 QLKSKFGKGYLLEIKVKESHQVDQIHNEIIRIFPHAARQDRFSSLLVYKIPMDNVQSLSQAFLLL 1559

  Fly   286 SVLQNMGKRRRSSIAQEIVEQVTVPAISNPALDMSDEQHAAEISGEF 332
            ...:........|.:|..:|||.:      .|....|:...|::..|
Frog  1560 EEAKRAYNIEEYSFSQSTLEQVFI------ELAKEQEKEDFELNNTF 1600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33970	NP_001034071.1	P-loop_NTPase	48..270	CDD:304359	70/232 (30%)
		CcmA	54..321	CDD:224054	81/320 (25%)
		ABC2_membrane_3	394..770	CDD:289468
		ABC2_membrane	<581..738	CDD:279410
abca10	XP_031750511.1	rim_protein	<107..1597	CDD:130324	92/367 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7652
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000